Femtosecond Laser Ablation in Developmental Biology
Femtosecond lasers are used for sub-cellular ablation. Several research groups
use femtosecond lasers to operate on living zebrafish embryo.
The UCLA Biophysics Neuroimaging Laboratory is committed to developing new microscopy techniques to further the reach of experimental methods in the area of systems neuroscience. The Lab is collaborating to develop next generation multi-photon microscopy systems, with the aim of imaging millimeter volumes of tissue with non-linear enhanced resolution at millisecond time scales. This may improve methods for analysis of in-vivo cortical circuits and classic microcircuit systems via calcium and potentiometric dyes, provide higher throughput for structural imaging, and enable more detailed modeling of systems of nerve cells. Calcium and potentiometric dyes can be used to monitor network activity with single cell and single spike resolution across hundreds of cells. Featured in the laboratory is an ultrafast Ti:Sa oscillator kit from Del Mar Photonics. Output power is typically hundreds of milliwatts. KLM Mode locking is started by voice coil and monitor high bandwidth avalanche photodiode combined with a lock-in amplifier. In this video Adrian Cheng shows his mltiphoton imaging system based on Del Mar Photonics Ti:Sapphire laser and describes his experiments on imaging of neural activity in zebra fish.
Engineers and biologists in the Ultrafast Optics and Nanophotonics Laboratory at
the University of Alberta have demonstrated the advantages of using femtosecond
lasers to manipulate molecules and cellular material inside living cells. In
experiments published in Biotechnology and Bioengineering, Vikram Kohli,
Abdulhakem Elezzabi, and colleagues used femtosecond laser pulses to perform
nanosurgery on living zebrafish embryos to introduce exogenous material into the
embryonic cells. Their findings should enhance researchers' ability to
noninvasively manipulate molecules in intracellular environments, a critical
component in advancing understanding of cellular structure and function.
Several methods have been used for introducing foreign substances into
developing embryos. However, microinjection and electroporation, the most
commonly used techniques, can be invasive and have some limitations. These
limitations are what prompted the researchers to use femtosecond laser pulses to
demonstrate the permeabilization of embryos for the delivery of foreign material
such as fluorescent probes, quantum dots, and plasmid DNA via transient pores.
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Related Publications
An all-optical approach for probing microscopic flows in living embryos. Supatto
W, Fraser SE, and Vermot J, Biophysical Journal, in press, (2008). pubmed
in vivo modulation of morphogenetic movements in Drosophila embryos with
femtosecond laser pulses. Supatto W, Débarre D, Moulia B, Brouzés E, Martin JL,
Farge E, and Beaurepaire E, PNAS, 102(4), 1047-1052 (2005). pubmed ("Research
Highlights" in Nature Methods, 2, 155 (2005)).
Quantitative multiphoton imaging and femtosecond pulse-induced ablation to study
mechano-sensitive gene expression during early Drosophila embryo development.
Supatto W, Paris VII / Institut Curie / Ecole Polytechnique, PhD Thesis (2005).
Tissue deformation modulates Twist expression to determine anterior midgut
differentiation in Drosophila embryos. Desprat N, Supatto W, Pouille PA,
Beaurepaire E, and Farge E, Developmental Cell, in press (2008).
Femtosecond pulse-induced microprocessing of live Drosophila embryos. Supatto W,
Débarre D, Farge E, and Beaurepaire E, Medical Laser Application, 20(3), special
issue on Laser nanoprocessing of biological targets (invited paper), 20(3),
207-216 (2005).
An all-optical approach to modulate and quantitatively analyse embryo
morphogenetic movements by using ultrashort laser pulses. Supatto W, Débarre D,
Moulia B, Farge E, and Beaurepaire E. Proc. SPIE - Imaging, Manipulation, and
Analysis of Biomolecules, Cells, and Tissues, 6088, 60881D (2006).
in vivo analysis of Drosophila embryo developmental dynamics by femtosecond
pulse-induced ablation and multimodal nonlinear microscopy. Supatto W, Débarre
D, Moulia B, Brouzés E, Martin JL, Schanne-Klein MC, Farge E, and Beaurepaire E,
Proc. SPIE - Multiphoton Microscopy in the Biomedical Sciences V, 5700, 256-264
(2005).
in vivo micro-dissection and live embryo imaging using two-photon microscopy to
study Drosophila melanogaster early developement. Supatto W, Brouzés E, Farge E,
and Beaurepaire E, Proc. SPIE - Femtosecond Laser Applications in Biology, 5463,
13-20 (2004).
V. Kohli and A. Y. Elezzabi, “Laser surgery of zebrafish (Danio rerio)
embryos using femtosecond laser pulses: Optimal parameters for exogenous
material delivery, and the laser’s effect on short- and long-term development "
BMC Biotechnology, 8,7 Feb. 2008.
K. J. Chau, Mark Johnson, and A. Y. Elezzabi, “Electron-Spin-Dependent Terahertz
Light Transport in Spintronic-Plasmonic Media,” Phys. Rev. Lett., 98,
133901-133904 (2007).
S. E. Irvine, P. Dombi, Gy. Farkas, and A. Y. Elezzabi, "Influence of
Carrier-Envelope Phase of Few-Cycle Pulses on Ponderomotive Surface-Plasmon
Electron Acceleration," Phys. Rev. Lett., 97, 146801-14684 (2006).
K. J. Chau, K. Rieckmann, and A. Y. Elezzabi, “Sub-Surface Probing of Terahertz
Particle Plasmons,” Appl. Phys. Lett., 90, 131114-131117 (2007).
K. J. Chau, C. Baron, and A. Y. Elezzabi, “Isotropic Photonic Magnetoresistance,”
Appl. Phys. Lett., 90, 121122 (2007).
M. C. Quong, and A. Y. Elezzabi, “Offset-Apertured Near-Field Scanning Optical
Microscope Probes,” Opt. Express 15, 10408-10420, (2007).
K. J. Chau, M. C. Quong, and A. Y. Elezzabi, “Terahertz Time-Domain
Investigation of Axial Optical Activity from a Sub-Wavelength Helix,” Opt.
Express 15, 3557-3567 (2007).
Vikram Kohli, Vanesa Robles , M. Leonor Cancela , Jason P. Acker , Andrew J.
Waskiewicz , and Abdulhakem Y. Elezzabi, “An Alternative Method for Delivering
Exogenous Material into Developing Zebrafish Embryos,” Biotechnol and Bioeng.,
98, 1230-1241 (2007).
K. J. Chau, K. Rieckmann, and A. Y. Elezzabi, “Metallic Phase Transition
Investigated via THz Time-Domain Spectroscopy,” Appl. Phys. Lett., 90, 041920
(2007).
G. D. Dice and A. Y. Elezzabi, “Random Lasing from a Nanoparticle-Based
Metal–Dielectric–Dye Medium,” J. Opt. A: Pure Appl. Opt., 9 186-193, (2007).
S. E. Irvine and A. Y. Elezzabi, "Ultracompact 180º Magnetic Spectrometer for
Intermediate Energy Electron Measurement," Meas. Sci. Tech., 17, 2455-2460,
(2006).
K. J. Chau and A. Y. Elezzabi, “Photonic Anisotropic Magnetoresistance in Dense
Co Particle Ensembles,” Phys. Rev. Lett., 96, 033903-033906, (2006).
K. J. Chau and A. Y. Elezzabi, “Effect of Interface Resistance on Terahertz
Pulses in Bimetallic Microparticles,” Phys. Rev. B 73, 085419-085425 (2006).
S. E. Irvine and A. Y. Elezzabi, “Surface-Plasmon-Based Electron Acceleration,”
Phys. Rev. A 73, 013815-013523 (2006).
S. E. Irvine and A. Y. Elezzabi, “Femtosecond Electron Pulse Gating Using
Surface Plasmons,” Opt. Express 4115-4127, (2006).
K. J. Chau, G. D. Dice, and A. Y. Elezzabi, “Coherent Plasmonic Enhanced
Terahertz Transmission through Random Metallic Media,” Phys. Rev. Lett., 94,
173904-173908 (2005).
G. D. Dice, S. Mujumdar , and A. Y. Elezzabi, “Plasmonically Enhanced Diffusive
and Subdiffusive Metal Nanoparticle-Dye Random Laser,” Appl. Phys. Lett., 86,
131105-131105, (2005).
K. J. Chau and A. Y. Elezzabi, “Terahertz Transmission Through Ensembles of
Sub-wavelength Size Metallic Particles,” Phys. Rev. B 72, 075110 (2005).
S. E. Irvine and A. Y. Elezzabi, “Ponderomotive Electron Acceleration Using
Surface Plasmon Waves Excited with Femtosecond Laser Pulses,” Appl. Phys. Lett.,
86, 264102-264105, (2005).
V. Kohli, A. Y. Elezzabi, and J. P. Acker, “Cell Nanosurgery Using Ultrashort
(Femtosecond) Laser Pulses: Applications to Membrane Surgery and Cell Isolation”
Laser Surg. Med., 37, 227-230, (2005).
V. Kohli, J. P. Acker, and A. Y. Elezzabi “Reversible Permeabilization Using
High-Intensity Femtosecond Laser Pulses: Applications to Biopreservation,”
Biotech. and Bioeng., 92, 889-899, (2005).
K. J. Chau, A. L. Dechant, and A. Y. Elezzabi, “High-Bandwidth Terahertz
Radiation from Ponderomotively Accelerated Carriers Using Bessel-Gauss
Femtosecond Pulses,” Appl. Phys. Lett., 86, 064106- 064109, (2005).
L. Dechant, S. K. Dew, S. E. Irvine, and A. Y. Elezzabi, “High-Transmission
Solid-Immersion Apertured Optical Probes for Near-Field Scanning Optical
Microscopy,” Appl. Phys. Lett., 86, 013102-013105, (2005).
S. E. Irvine , A. L. Dechant, and A. Y. Elezzabi, “Generation of 0.4-keV
Femtosecond Electron Pulses Using Impulsively Excited Surface Plasmons,” Phys.
Rev. Lett., 93, 184801-184804, (2004).
S. Mujumdar, K. J. Chau, and A. Y. Elezzabi, “Experimental and Numerical
Investigation of Terahertz Transmission through Strongly Scattering
Sub-wavelength Size Spheres,” Appl. Phys. Lett., 85, 6284-6286, (2004).
S. Mujumdar, G. Dice, and A. Y. Elezzabi, “Few Cycle Pulse Propagation in
Multiple Scattering Media,” Opt. Comm., 247, 19-27, (2005).
L. Dechant and A. Y. Elezzabi, “Femtosecond Optical Pulse Propagation in
Subwavelength Metallic Slits,” Appl. Phys. Lett., 84, 4678- 4678, (2004).
K. J. Chau and A. Y. Elezzabi, “Two-Dimensional Drift-Diffusion Analysis of
Magnetic Field Enhanced THz Emission from Semiconductor Surfaces,” Opt. Comm.,
242, 295-304, (2004).
K. J. Chau, S. E. Irvine, and A. Y. Elezzabi, “A Gigahertz Surface Magneto-Plasmon
Optical Modulator,” IEEE J. Quantum Electron., vol. 40, 571-579, (2004).
J. F. Holzman and A. Y. Elezzabi, “ Two-Photon Photoconductive Terahertz
Generation in ZnSe,” Appl. Phys. Lett., 83, 2967-2969 (2003).
J. F. Holzman and A. Y. Elezzabi, "Dispersion-Free High-Speed Beam Chopper for
Ultrafast Pulsed Laser Applications," Meas. Sci. Tech. 14, pp. N41-N44 (2003).
S. E. Irvine and A. Y. Elezzabi, "A Miniature Broadband Bismuth-Substituted
Yttrium Iron Garnet Magneto-Optic Modulator," Journal of Physics D: Applied
Physics, Special Issue: The subject interface between magnetism and photonics,
vol. 36, pp. 2218-2221 (2003).
S. E. Irvine and A. Y. Elezzabi, "Wideband Magneto-Optic Modulation in a
Bismuth-Substituted Yttrium Iron Garnet Waveguide," Optics Communications, vol.
220, pp. 325-329 (2003).
A. Y. Elezzabi and S. E. Irvine, "Parametrically Driven First-Order Suhl
Instability and Nonlinearitites in Bismuth-Substituted Yttrium Iron Garnet
Films," Appl. Phys. Lett., vol. 82, pp. 2464-2466 (2003).
A. Y. Elezzabi and J. F. Holzman, "Photoconductive Generation and Detection of
Guided-Wave and Free-Space Terahertz Waveforms," IEICE Transactions on
Electronics E86C, pp. 1218-1225 (2003). (Invited)
J. F. Holzman, S. E. Irvine, F. E. Vermeulen, A. Y. Elezzabi, "Free-Space
Detection of Terahertz Radiaton Using Crystalline and Polycrystalline ZnSe
Electro-optic Sensors," Appl. Phys. Lett., 81, 2294 (2002).
S. E. Irvine and A. Y. Elezzabi, “Modeling of High-Speed Magneto-Optic Beam
Deflection,” IEEE Jour. Quantum Elec., 38, 1428, (2002).
S. E. Irvine and A. Y. Elezzabi, “Multi-Gigahertz Guided Wave Magneto-Optic
Modulator,” IEEE Photonics Technol. Lett., 14, 798, (2002).
M. D. Cummings, J. F. Holzman, and A. Y. Elezzabi, “Carrier Transport Dynamics
in an Edge-Illuminated Photoconductive Switch,” J. Vac. Sci. Technol., A20,
1057, (2002).
J. F. Holzman, F. E. Vermeulen, and A. Y. Elezzabi, “Generation of 1.2 ps
Electrical Pulses Through Parallel-Gating in Ultrathin Silicon Photoconductive
Switches,” Appl. Phys. Lett., 79, 4249-4252, (2001).
M. D. Cummings and A. Y. Elezzabi, “Ultrafast Impulsive Excitation of Coherent
Longitudinal Acoustic Phonon Oscillations in Highly Photoexcited InSb,” Appl.
Phys. Lett., 79, 770-772, (2001).
M. D. Cummings, J. F. Holzman, and A. Y. Elezzabi, “Femtosecond Carrier
Dynamics in an Asymmetrically Excited GaAs Photoconductive Switch,” Appl. Phys.
Lett.,78, 3535-3537, (2001).
J. F. Holzman, F. E. Vermeulen, and A. Y. Elezzabi, “Frozen Wave
Generation of Bandwidth-Tunable Two-Cycle THz Radiation,” J. Opt. Soc. Am. B,
17, 1457-1463, (2000).
J. F. Holzman, F. E. Vermeulen, B. W. Arnold, and A. Y. Elezzabi,
“Photoconductive Gating of Picosecond Electrical Pulses on Thinned Si-Substrates,”
Electronics Lett., 36, 1225-1226, (2000).
J. F. Holzman, F. E. Vermeulen, and A. Y. Elezzabi,
“Recombination-Independent Photogeneration of Ultrashort Electrical Pulses,”
Appl. Phys. Lett., 76, 134-136, (2000).
J. F. Holzman, F. E. Vermeulen, and A. Y. Elezzabi, “Ultrafast
Photoconductive Self-Switching of Subpicosecond Electrical Pulses,” IEEE J.
Quantum Electron, 36, 130-136, (2000).
A. Y. Elezzabi, J. F. Holzman, J. Sit, K. Robbie, and M. J. Brett, “Thin
Film Vertical Diffraction Gratings Fabricated Using Glancing Angle Deposition,”
Electronics Letters, 35, 491-493, (1999).
J. F. Holzman, F. E. Vermeulen, and A. Y. Elezzabi, “Ultrafast All-Optical
Modualtion of Infrared Radiation Via Metal-Semiconductor Waveguide Structures,”
IEEE J. Quantum Electron, 35, 583-589, (1999).
G. M. Steeves, A. Y. Elezzabi, R. Teshima, R. A. Said, and M. R. Freeman,
“Circuit Analysis of an Ultrafast Junction Mixing Scanning Tunneling
Microscope,” IEEE J. Quantum Electron., 34, 1415-1418, (1998).
G. M. Steeves, A. Y. Elezzabi, and M. R. Freeman, “Nanometer-Scale Imaging
with an Ultrafast Scanning Tunneling Microscope,” Appl. Phys. Lett. 72, 504-506
(1998).
G. M. Steeves, A. Y. Elezzabi, and M. R. Freeman, “Advances in Picosecond
Scanning Tunneling Microscopy Via Junction Mixing,” Appl. Phys. Lett., 70,
1909-1911, (1997).
M. R. Freeman, A. Y. Elezzabi, and J. A. H. Stotz, “Current Dependence of
the Magnetization Rise Time in Thin Film Heads”, J. Appl. Phys., 81, 4516-4518,
(1997).
M. R. Freeman, A. Y. Elezzabi, G. M. Steeves, G. Nunes, Jr., “Ultrafast
Time-resolution in Scanning Tunneling Microscopy,” Surface Sci., 386, 290-900,
(1997).
A. Y. Elezzabi and M. R. Freeman, “Ultrafast Magneto-Optic Sampling of
Picosecond Current Pulses,” Appl. Phys. Lett., 68, 3546-3548, (1996).
A. Y. Elezzabi, M. R. Freeman, and Mark Johnson, “Direct Measurement of
the Conduction Electron Spin-Lattice Relaxation Time T1 in Gold,” Phys. Rev.
Lett., 77, 3220-3224, (1996).
A. Y. Elezzabi, M. K. Y. Hughes, J. Meyer, and S. R. Johnson, “Ultrafast
Measurement of Nonequilibrium Carrier Lifetime in In0.85Ga0.15As/GaAs Relaxed
Superlattice Structure,” Opt. Lett., 20, 587-589, (1995).
J. Meyer, A. Y. Elezzabi, and M. K. Y. Hughes, “Infrared Absorption and
Momentum Relaxation of Free Carriers in Silicon Generated by Subpicosecond Above
Band Gap Radiation,” IEEE J. Quantum Electron., 31, 729-734, (1995).
J. Meyer, A.Y. Elezzabi, and M. K. Y. Hughes, “An Investigation of
Ultrafast Plasma Dynamics in a GaAs Infrared Reflection Switch,” IEEE J. Quantum
Electron., 31, 1292-1301, (1995).
A. Y. Elezzabi, J. Meyer, and M. K. Y. Hughes, “600 fs 10.6 mm Infrared
Pulse Generation with Radiation-Damaged GaAs Reflection Switch,” Appl. Phys.
Lett., 66, 402-404, (1995).
H. Houtman, A. Cheuck, A. Y. Elezzabi, J. E. Ford, M. Laberge, W. Liese,
J. Meyer, G. C. Stuart, and Y. Zhu, “High-Speed Circuits for TE Discharge Lasers
and High Voltage Applications,” Rev. Sci. Instrum., 64, 839-853, (1994).
A. Y. Elezzabi, J. Meyer, M. K. Y. Hughes, and S. R. Johnson, “Generation
of 1-ps Infrared Pulses at 10.6 um by Use of Low-Temperature-Grown GaAs as an
Optical Semiconductor Switch,” Opt. Lett., 19, 898-900, (1994).
. Y. Elezzabi and J. Meyer, “All-Optical Time-Division Demultiplexer Using
Semiconductor Switching,” Appl. Opt., 33, 3635-3641, (1994).
Y. Elezzabi, H. Houtman, and J. Meyer, “Time-Resolved Impact Ionization in
ZnSe High-Voltage Switches,” IEEE Trans. on Plasma Science, 22, 1043-1048,
(1994).
Y. Elezzabi and J. Meyer, “Simulation of the Generation of Ultrafast
Mid-Infrared Laser Pulses,” IEEE J. Quantum Electron., 28, 1830-1834, (1992).
J. Meyer and A. Y. Elezzabi, “Subpicosecond Reflection Switching of 10 um
Radiation Using Semiconductor Surfaces,” Appl. Phys. Lett., 58, 1940-1943,
(1991).
J. Meyer and A. Y. Elezzabi, “Experimental Study of the Electron Density
and Discharge Dynamics in a XeCl Excimer Laser ,” J. Appl. Phys., 68, 3838-3843,
(1990).
Other Publications
A. Y. Elezzabi, K. J. Chau, C. A. Baron, and Mark Johnson, “Discovering
Spinplasmonics,” Proc. SPIE Int. Soc. Opt. Eng., (Invited), (in print).
Vikram Kohli and A. Y. Elezzabi, “Femtosecond Laser Pulse Surgery and
Transfection in Embryos,” Proc. SPIE Int. Soc. Opt. Eng., (Invited), (in print).
K. J. Chau, M. C. Quong, and A. Y. Elezzabi, “Ultrafast Terahertz Electric Field
Polarization Dynamics in Metallic Mesostructures, Proc. SPIE Int. Soc. Opt.
Eng., 6471, 64710P (2007), (Invited)
C. A. Baron, K. J. Chau, and A. Y. Elezzabi, “Terahertz Isotropic Photonic
Magnetoresistance,” Proc. SPIE Int. Soc. Opt. Eng., 6471, 64710N (2007)
(Invited).
A. Y. Elezzabi, “Spinplasmonics: A New Route for Active Plasmonics,” Proc. SPIE
Int. Soc. Opt. Eng. 6441, 6641-57 (2007), (Invited)
K. J. Chau and A. Y. Elezzabi, “Extraordinary Single Cycle Terahertz
Transmission through Ensembles of Sub-Wavelength Size Metal Particles,” Proc.
SPIE Int. Soc. Opt. Eng., 6118, 61180L-1 (2006), (Invited).
K. J. Chau and A. Y. Elezzabi, “Photonic Anisotropic Magnetoresistance in
Sub-Wavelength Size Co Particles,” Proc. SPIE Int. Soc. Opt. Eng., 6118,
61180M-1 (2006), (Invited).
Kenneth J. Chau and A. Y. Elezzabi, “A Two-Dimensional Drift-Diffusion Model of
THz Emission from n-GaAs and InAs Surfaces in a Magnetic Field” Proc. SPIE Int.
Soc. Opt. Eng., 5725, 61 (2005), (Invited).
A. Y. Elezzabi and J. F. Holzman, "Photoconductive Generation and Detection of
Guided-Wave and Free-Space Terahertz Waveforms," IEICE Transactions on
Electronics E86C, pp. 1218-1225, 2003. (Invited)
J. F. Holzman, M. D. Cummings, and A. Y. Elezzabi, "Terahertz Photonics:
Ultrafast Physics and Applications," Proc. SPIE, 4833, Applications of Photonic
Technology 5, 85-96, (2003), (Invited).
Vikram Kohli and A. Y. Elezzabi, “Part I: Embryonic Surgery Using Femtosecond
Laser Pulses for the Delivery of Exogenous Materials and the Analysis of Gene
Expression,” Proc. SPIE, 2008 (accepted and in print).
Vikram Kohli and A. Y. Elezzabi, “Part II: Morphological Analysis of Embryonic
Development Following Femtosecond Laser Manipulation,” Proc. SPIE, 2008
(accepted and in print).
C. A. Baron and A. Y. Elezzabi, “Time- and Angular-Resolved Terahertz
Spectroscopy” Proc. SPIE, 2008 (accepted and in print).
Vikram Kohli, Deli Yu, and Abulhakem Y. Elezzabi, “ Laser-Assisted Ablation of
Corneal-Like Material Using Focused Femtosecond Laser Pulses,” Proc. SPIE, 6460,
6460-D, 2007.
K. J. Chau, Mark Johnson, and A. Y. Elezzabi, “Merging Spintronics and
Plasmonics,” Conference on Lasers and Electro-Optics Tech. (APS, IEEE, OSA),
Baltimore , Maryland , May 6-11, 2007, (Postdeadline Digest-CPDA5).
K. J. Chau and A. Y. Elezzabi, THz Phase Transition Spectroscopy of Metals,
Conference on Lasers and Electro-Optics Tech. Digest (APS, IEEE, OSA), JFB1,
Baltimore, Maryland, May 6-11, 2007.
Michael C. Quong and Abdulhakem Y. Elezzabi, “An Offset-Apertured Probe: a
Hybrid Apertured and Scattering-Type Near-Field Scanning Optical Probe,”
Conference on Lasers and Electro-Optics Tech. Digest (APS, IEEE, OSA), JThD58,
Baltimore , Maryland , May 6-11, 2007.
C. A. Baron, K. J. Chau, and A. Y. Elezzabi, “Isotropic Photonic
Magnetoresistance: A New Phenomenon at Terahertz Frequencies,” Conference on
Lasers and Electro-Optics Tech. Digest (APS, IEEE, OSA), JFB3, Baltimore ,
Maryland , May 6-11, 2007.
K. J. Chau and A. Y. Elezzabi, “Investigations on the Origin of the Terahertz
Transmission through Random Metallic Media,” Conference on Lasers and
Electro-Optics Tech. Digest (APS, IEEE, OSA), JtuD23, Long Beach , CA , May
21-26, 2006.
G. D. Dice, K. J. Chau, and A. Y. Elezzabi, “Surface Plasmon Enhanced Metal
Nanoparticle-Dye Random Laser,” Conference on Lasers and Electro-Optics Tech.
Digest (APS, IEEE, OSA, 2006), CMFF6, Long Beach, CA, May 21-26, 2006.
K. J. Chau and A. Y. Elezzabi, “Contact Resistance Dynamics at Bimetallic
Interfaces Investigated by Ultrafast Terahertz Surface Plasmon-Mediated
Transmission Spectroscopy,” Proc. SPIE, 6118, 61184- (1-9), 2006.
K. J. Chau and A. Y. Elezzabi, “Near-Field Mediated Terahertz Transmission
through Random Media,” Conference on Lasers and Electro-Optics Tech. Digest (APS,
IEEE, OSA), CMI5, Long Beach , CA , May 21-26, 2006.
G. D. Dice, K. J. Chau, and A. Y. Elezzabi, “Surface Plasmon Enhanced Metal
Nanoparticle-Dye Random Laser,” Conference on Lasers and Electro-Optics Tech.
Digest (APS, IEEE, OSA), Long Beach, CA, May 21-26, 2006.
Vikram Kohli, Jason P. Acker, and Abdulhakem Y. Elezzabi, “Permeabilization and
Cell Surgery Using Femtosecond Laser Pulses: an Emerging Tool for Cellular
Manipulation,” Optical Interactions with Tissue and Cells XVII, Proc. SPIE 6084,
608414 (2006).
S. E. Irvine and A. Y. Elezzabi, “Generation of 2 keV, 30 fs Electron Pulses via
Surface Plasmon Waves,” Conference on Lasers and Electro-Optics Tech. Digest (APS,
IEEE, OSA) Baltimore, Maryland, May 22-27, 2005.
K. J. Chau and A. Y. Elezzabi, “Broadband Terahertz Pulse Propagation in
Strongly Scattering Random Media,” Conference on Lasers and Electro-Optics Tech.
Digest (APS, IEEE, OSA) Baltimore , Maryland , May 22-27, 2005.
K.J. Chau, S. Mujumdar , and A.Y. Elezzabi, “Terahertz Propagation in
Non-Homogeneous Highly Scattering Media,” Proc. SPIE, 5727, 177-185 (2005).
K. J. Chau and A. Y. Elezzabi, “Ultra-wide Bandwidth THz Emission from
Semiconductor Irradiated with Intense Radially Polarized, Bessel-Gauss Pulses,”
Ultrafast Phenomena XIV, Eds. T. Kobayashi, T. Okada, T. Kobayashi, Keith A.
Nelson, and S. DeSilvestri, Springer Series in Chemical Physics 667-669, (2004).
S. E. Irvine and A. Y. Elezzabi, “Surface Plasmon Assisted 26, 0.4 keV Electron
Pulse Generation,” Ultrafast Phenomena XIV, Eds. T. Kobayashi, T. Okada, T.
Kobayashi, Keith A. Nelson, and S. DeSilvestri, Springer Series in Chemical
Physics 708-710, (2004).
A. L. Dechant and A. Y. Elezzabi, “Plasmon Enhanced Ultrafast Optical
Transmission in Metallic Nano-Arrays,” Ultrafast Phenomena XIV, Eds. T.
Kobayashi, T. Okada, T. Kobayashi, Keith A. Nelson, and S. DeSilvestri, Springer
Series in Chemical Physics 658-660, (2004).
K. J. Chau, S. E. Irvine, and A. Y. Elezzabi, “High-Speed Surface Magneto-Plasmon
Reflectivity Modulator,” OSA Conference on Lasers and Electro-Optics Tech.
Digest (APS, IEEE, OSA), San Francisco, CA, May 16-21, (2004)
S. E. Irvine and A. Y. Elezzabi, "Polarization-Selective Optical Beam Deflection
Using Magnetically Activated Bi-YIG Films,” Proc. of SPIE, 5260, 585-590 (2003).
S. E. Irvine and A. Y. Elezzabi, "Parametric Excitation of Spin Waves in
Bismuth-substituted Yttrium Iron Garnet Films Using the First-Order Suhl
Instability," Proc. Int. Conf. on MEMS, NANO, and Smart Systems, Banff, AB,
148-152, 2003.
S. E. Irvine and A. Y. Elezzabi, "Broadband Optical Modulation Using
Magneto-Optic Bi-YIG Thin Films," Proc. of SPIE, 5260, 580-584 (2003).
M. D. Cummings and A. Y. Elezzabi, “Photo-excitation of Coherent Acoustic
Phonons in InSb,” Ultrafast Phenomena XIII, Eds. R. D. Miller, M. M. Murnane, N.
F. Scherer, and A. M. Weiner, Springer Series in Chemical Physics, 383-386,
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