Del Mar Photonics at SPIE Defense, Security +Sensing SPIE DSS conference
13 - 17 April 2009
Orlando World Center Marriott Resort & Convention Center
Orlando, FL United States
Instruments for Nanotechnologies
AFM HERON
Near-field
Scanning Optical Microscope (NSOM)
Femtosecond nanophotonics
Femtosecond NSOM
Nanotechnology related presentations - Femtosecond related presentations
Nanothermites for space and defence applications (Poster Presentation)
Paper 7314-23 of Conference 7314
Authors(s): Marc Comet, Denis Spitzer, Jean-Pierre Moeglin, Institut Franco-Allemand
de Recherches de Saint-Louis (France)
Date: Tuesday, 14 April 2009
In this presentation, three examples of nanothermites will be given in order to
illustrate the contribution of these nanomaterials in the future spatial and
defence applications:
- the incidence of the size of the metallic oxide particles on the reactivity is
illustrated by the case of WO3/Al nanothermites,
- the correlation between the composition/structure of the oxide phase and the
reactivity was achieved on AlxMoyOz/Al nanothermites,
- the fabrication of Gas Generating Nanothermites was performed by adding
military explosives in porous mineral oxides used to fabricate nanothermites.
Micro/nanomanufactured THz electromagnetic metamaterials as a base for
applications in transportation (Paper Presentation)
Paper 7314-15 of Conference 7314
Authors(s): Herbert O. Moser, National Univ. of Singapore (Singapore)
Date: Monday, 13 April 2009
Electromagnetic metamaterials (EM3) have been considered for a variety of
applications in automotive transportation from radar to night vision at THz and
optical frequencies. Using rod-split-ring or S-string designs, SSLS has
developed high-aspect-ratio and free-standing EM3 from 1 THz upwards. In
free-standing EM3, S-strings are freely suspended by window-frames and will,
eventually, become self-supported grids. Window-frame-held chips already cover a
comparably large area of 56 mm2. As the refractive index may vary from positive
to negative, spectral and spatial properties of filters, absorbers, reflectors,
and antennae may be tailored, making such materials a potential "tool kit" for
applications in transportation.
Metal-coated Si nanograss as highly sensitive SERS sensors (Paper Presentation)
Paper 7312-17 of Conference 7312
Authors(s): Jing Tang, Fung-Suong Ou, Huei-Pei Kuo, Hewlett-Packard Labs.
(United States); William F. Stickle, Hewlett-Packard Co. (United States);
Shih-Yuan Wang, Wei Wu, Zhiyong Li, R. Stanley Williams, Hewlett-Packard Labs.
(United States)
Date: Monday, 13 April 2009
Surface enhanced Raman scattering (SERS) has attracted great attention due to
its tremendous potential for chemical and biomolecular sensing. We created novel
SERS substrates by metalization (Ag or Au) of Si nanograss fabricated by a Bosch
process on single crystalline silicon. The dependence of the SERS effect on the
surface morphology and topology of the substrate prior to metal deposition
(controlled by the process parameters such as etching time and oxygen flow rate)
and on the thickness of the metal deposition was thoroughly studied in order to
optimize the SERS signals. We demonstrated that the fabricated SERS substrates
are highly sensitive and can produce more than 10 times higher SERS signals than
the commercially available SERS substrate. No template or lithography was used
in making such substrates, thus providing a simple and inexpensive method to
achieve highly sensitive large-area SERS substrates.
Nanosurgeon (Paper Presentation)
Paper 7343-27 of Conference 7343
Authors(s): Huan-Yao Lei, National Cheng Kung Univ. (Taiwan); Ching-An Peng,
Nanyang Technological Univ. (Taiwan); Ming J. Tang M.D., National Cheng Kung
Univ. (Taiwan); Harold H. Szu, Naval Surface Warfare Ctr. (United States); Kitt
C. Reinhardt, Air Force Office of Scientific Research (United States)
Date: Wednesday, 15 April 2009
We explore a nano-surgeon enabled by nano-manipulator to eradicate the point
tumors.
Preliminary results will be presented.
A nanocontact cross-junction diode for rectenna (Poster Presentation)
Paper 7318-52 of Conference 7318
Authors(s): Onejae Sul, Rajen Dutta, Eui-Hyeok Yang, Stevens Institute of
Technology (United States)
Date: Thursday, 16 April 2009
An MIM, Metal-Insulator-Metal, diode is known as best one among many kinds of
diodes, for high frequency rectification purpose such as light energy
collection, due to fast electron tunneling. For better rectification and energy
harvesting efficiency, two new approaches are taken. By using MIIM structure,
better non-linearity is expected. The cut-off frequency of a diode is determined
by the cross-section area of it. By using cross-junction of two nanowires, diode
cross-section will be minimized under 10 by 10 nm for visible light frequency.
The use of linear covariance techniques in the evaluation of nanosatellite
attitude determination system accuracy (Paper Presentation)
Paper 7330-5 of Conference 7330
Authors(s): Rollin R. Fullmer, Utah State Univ. (United States); Klaus-Juergen
Schilling, Univ. Würzburg (Germany); Anders Forslund, David Geller, Alexander
Nucera, Utah State Univ. (United States)
Date: Tuesday, 14 April 2009
An analysis method for estimating the attitude determination accuracy of a
nanosatellite during the design phase is introduced. The software tool “Aforce”,
which implements a Linear Covariance analysis technique, is presented. This
method singles out the error contribution made by each modeled error source.
This ability provides a designer with rapid attitude accuracy estimates
resulting from design changes. Examples including the selection of better
sensors, ground calibration tests, and the inclusion of additional states in the
Kalman filtering algorithm for two satellites will be presented.
Nanomaterial sensing (Paper Presentation)
Paper 7343-26 of Conference 7343
Authors(s): Francisco Santiago, Harold H. Szu, NSWCDD (United States)
Date: Wednesday, 15 April 2009
We review nanomaterial for sensing of EOIR. It provides a powerful messo-scale
interface between macroscopic world that we live and the microscopic world that
atoms live.
Nanoengineering Award presentation (Paper Presentation)
Paper 7343-33 of Conference 7343
Authors(s): Robert D. Shull, National Institute of Standards and Technology
(United States)
Date: Wednesday, 15 April 2009
No description available
Engineering nanopatterned surfaces for real-time colorimetric detection of
biochemical agents (Paper Presentation)
Paper 7318-17 of Conference 7318
Authors(s): Ashwin Gopinath, Gary F. Walsh, Sylvanus Y. Lee, Svetlana V.
Boriskina, Luca Dal Negro, Boston Univ. (United States); Jason Amsden, David L.
Kaplan, Fiorenzo G. Omenetto, Tufts Univ. (United States)
Date: Wednesday, 15 April 2009
In this talk, we will discuss the design, nanofabrication and optical scattering
characterization of novel colorimetric bio-sensors based on sensitive color
change and light localization in nano-textured surfaces base on biocompatible
optical materials. Our approach hinges on the integration of photonic crystal
optics, top-down nanofabrication techniques (electron-beam lithography) and
direct nano-imprint lithography for the nanoscale control of the colorimetric
response (light scattering) from chip-scale structures capable of for real-time
biochemical detection.
Lanthanide-halide-based nanoscintillators for portable radiological detectors
(Paper Presentation)
Paper 7306A-46 of Conference 7306A
Authors(s): Marek Osinski, Krishnaprasad Sankar, Nathan J. Withers, John B.
Plumley, Antonio C. Rivera, Brian A. Akins, Gennady A. Smolyakov, The Univ. of
New Mexico (United States)
Date: Thursday, 16 April 2009
Lanthanum fluoride nanocrystals doped with various concentrations of cerium were
synthesized using colloidal approach. The nanocrystals were characterized by
transmission electron microscopy, scanning electron microscopy, energy
dispersive spectroscopy (EDS), steady state UV-visible optical absorption and
photoluminescence spectroscopy, and by photoluminescence lifetime and quantum
efficiency measurements. The radiation hardness of the synthesized material was
tested using a 137Cs gamma source. Scintillation was observed from the LaF3:Ce
nanocrystals exposed to low-level gamma irradiation.
Lead-iodide-based nanoscintillators for detection of ionizing radiation (Paper
Presentation)
Paper 7304-61 of Conference 7304
Authors(s): Nathan J. Withers, Brian A. Akins, Antonio C. Rivera, John B.
Plumley, Gennady A. Smolyakov, Marek Osinski, The Univ. of New Mexico (United
States)
Date: Thursday, 16 April 2009
A variety of lead-iodide-based nanocrystals of interest as detectors of ionizing
radiation were synthesized using colloidal approach. The nanocrystals were
characterized by transmission electron microscopy, scanning electron microscopy,
energy dispersive spectroscopy (EDS), steady state UV-visible optical absorption
and photoluminescence spectroscopy, and by photoluminescence lifetime and
quantum efficiency measurements. The radiation hardness of the synthesized
material was tested using a 137Cs gamma source. Scintillation was observed from
the lead-iodide based nanocrystals exposed to low-level gamma irradiation.
Nanosensor design for hydrogen detection (Poster Presentation)
Paper 7318-56 of Conference 7318
Authors(s): Peng Zhang, Abihilash Vincent, Sudipta Seal, Hyoung Cho, Univ. of
Central Florida (United States)
Date: Thursday, 16 April 2009
In this work, we present the design parameters and optimization of the nanoscale
gap interdigitated electrodes (IDEs) for hydrogen gas sensing. In order to
extract important design parameters and understand the sensor performance,
numerical analysis has been carried out for calculating the effect of electrical
field on the sensor characteristics. The optimized design of IDEs with 50 nm in
gap and 1,000 nm in width shows the change of electrical field in the thickness
direction is much reduced. It is expected that this design responds better to
conductance change on top surface and leads to shorter response time.
Nanosurfaces for nanosensing (Paper Presentation)
Paper 7318-37 of Conference 7318
Authors(s): Edward Gillman, Alexander S. Raspopin, David Costello, Senspex
(United States)
Date: Friday, 17 April 2009
Nanoscale electric field confinement and enhancement is a well known phenomenon
for small particles and flat interfaces. Senspex is using e-beam lithography to
develop nanosensors for the detection of biological and chemical hazards. The
sensors that are being developed are a square array of metallic cubes; each cube
has dimensions of approximately 100nm x 100nm x 30nm and a pitch of 125nm in the
x- and y-directions. Senspex’s numerical simulations show that the intense
electric field in the minute volume between the cubes will lead to a high
probability of detection for small concentrations of analyte in real world
situations.
Nanoscale structure-activity relationships in the treatment of disease (Paper
Presentation)
Paper 7313-1 of Conference 7313
Authors(s): Daniel Feldheim, Univ. of Colorado at Boulder (United States)
Date: Thursday, 16 April 2009
We have recently documented the use of an inorganic nanocrystal-based approach
for the inhibition of HIV infection. The inhibitor was a 2.0 nm diameter gold
nanocrystal displaying 12 copies of an organothiol ligand. The ligand itself was
completely inactive toward the inhibition of HIV-1 infection; however upon
conjugation of the ligand to a 2.0 nm diameter gold nanocrystal, we were able to
create gold nanocrystal conjugates that were equipotent to some of the best HIV
fusion inhibitors. These results have inspired us to think in new ways about
gold nanocrystal-based therapeutic design. This talk will describe some of these
considerations.
Surface-enhanced Raman scattering performance of rough metallic nanowire-based
devices (Paper Presentation)
Paper 7318-12 of Conference 7318
Authors(s): Stergios J. Papadakis, Joan A. Hoffmann, The Johns Hopkins Univ.
Applied Physics Lab. (United States); JiaHai Wang, Pawan Tiyagi, David H.
Gracias, The Johns Hopkins Univ. (United States)
Date: Wednesday, 15 April 2009
We grow rough metallic nanowires and test them using a scanning micro-Raman
spectrometer for SERS performance for a range of simulants for chemical agents
and biomarkers. Looking at hundreds of individual nanowires, we find that
certain surface morphologies result in over 30% of the nanowires producing
enhancement from 10^5 to 10^7.
The nanowires are electrochemically grown in alumina templates, which have
smooth walls. Various methods of creating rough nanowires are discussed,
including techniques which modify the template surfaces to generate the
roughness during growth and post-processing techniques applied after the
nanowires are released from the template.
Physical and chemical sensing based on micro- and nanotechnologies (Keynote
Presentation) (Keynote)
Paper 7333-2 of Conference 7333
Presenter(s): Panos Datskos, Univ. of Tennessee (United States)
Date: Monday, 13 April 2009
No description available
Ultra-high-sensitivity nanoplasmonic resonance energy transfer spectroscopic
biomolecular imaging (Paper Presentation)
Paper 7312-3 of Conference 7312
Authors(s): G. Logan Liu, Univ. of Illinois at Urbana-Champaign (United States)
Date: Monday, 13 April 2009
Nanoplasmonic resonance spectroscopy enhances sensitivity and throughput of
conventional SPR detection technique while still suffers with modest molecular
specificity. Here we demonstrated a new sensing technique --- nano plasmonic
resonance energy transfer (PRET) spectroscopy to detect complex biomolecular
activities including conformational change, electron transfer and protein
interactions with ultrahigh sensitivity and specificity. Compared to FRET
sensing technology, PRET has much stronger optical signal to noise ratio and
minimal photobleaching problems. Nano PRET spectroscopic molecular imaging
technique can be used in multiplexed label-free cancer biomarker detections and
environmental sensing applications.
Demonstration of flexible nanocomposite NIR mirror (Paper Presentation)
Paper 7298-38 of Conference 7298
Authors(s): Thad L. Druffel, Optical Dynamics Corp. (United States)
Date: Monday, 13 April 2009
Thin film metal oxide coatings have been used commercially for electromagnetic
filters from the UV to infra red regions for over half a century. Deposition
onto a substrate has typically been accomplished using vapor deposition
techniques and more recently sol-gel methods. These coatings provide very good
optical performance under abrasion, thermal cycles and variable humidity when
applied on substrates with similar thermal and mechanical properties. When
conventional metal oxide coatings are applied to flexible, relatively soft
substrates such as polymers, mismatches in mechanical properties can reduce
interfacial adhesion or accelerate mechanical failures.
Nanofluidic biochips for use in the direct THz spectroscopic detection and
identification of biological species (Paper Presentation)
Paper 7312-20 of Conference 7312
Authors(s): Edgar A. Mendoza, Redondo Optics, Inc. (United States)
Date: Monday, 13 April 2009
Optical based nanolithography is an enabling tool for the cost-efficient,
high-throughput production of nanofluidic biochip sensor platforms that can be
used for the detection and identification of biological materials and agents
using integrated THz-frequency spectroscopic techniques. This paper describes
preliminary experimental results obtained with the goal of developing accurate
and sensitive THz characterization of aqueous biological samples diffusing
through the channels of nanofluidic biochips produced using optical
nanolithography techniques.
Heterogeneous 3D integration of multispectral photonic sensor with highly
oriented micro/nanopillars of semiconductors (Paper Presentation)
Paper 7318-4 of Conference 7318
Authors(s): M. Saif Islam, Univ. of California, Davis (United States)
Date: Wednesday, 15 April 2009
We developed a novel method for three-dimensional heterogeneous integration of
devices based on any semiconductor material on a pliant surface with arbitrary
surface profile. Arrays of optical detectors in the form of vertically oriented
micro/nano-pillars with diverse bandgaps and physical properties are fabricated
via synthetic bottom-up or transformative top down approaches on a single
crystal surface and then transferred to a different target surface using a
polymer assisted shear-fracturing process. The original wafers are used
repeatedly for generating more devices and are never consumed. Ohmic contacts
with low contact resistance are formed for individual electrical addressing of
each layer of sensors using metals and/or conducting polymer such as PANI and
PEDOT:PSS. The method offers an opportunity for device fabrication with low fill
factor contributing to lower dark current, reduced parasitic capacitance and
higher efficiency of light absorption.
Microfluidic and nanofluidic integration of plasmonic substrates for biosensing
(Paper Presentation)
Paper 7322-5 of Conference 7322
Authors(s): David Sinton, Alexandre G. Brolo, Reuven Gordon, Univ. of Victoria
(Canada)
Date: Thursday, 16 April 2009
Metallic nanohole arrays support surface electromagnetic waves that enable
enhanced optical transmission and may be exploited for sensing. Our recent work
in this area is described here. First, using a blocking layer to limit the
exposed metal surface to the in-hole region is found to result in effective
sensing in a much smaller, nanoconfined volume. Second, efforts to improve the
optical detection are described including biaxial nanohole arrays and
intensity-based multiplexed sensing. Third, the fluidic integration and
transport aspects of on-chip nanohole array sensors are discussed. A
flow-through nanohole array shows benefits with respect to reactant transport
and sensor functionalization.
MEMS and nanotechnologies from devices to systems: DARPA's perspectives (Keynote
Presentation) (Keynote)
Paper 7318-27 of Conference 7318
Presenter(s): Amit Lal, Defense Advanced Research Projects Agency (United
States)
Date: Thursday, 16 April 2009
The core of MEMS technology is the capability to form chip-integrated micro
beams, cantilevers, and plates. DARPA has mined MEMS technology in an effort to
provide increased performance and functionality to integrated circuits. MEMS
allows one to use reduced mass for increased resonance frequencies in
micro-resonators; craft long and thin high aspect ratio structures for high
thermal resistances; and generate huge surface-to-volume ratios for increased
interaction with the environment. This talk will describe recent programs
undertaken to exploit fundamental building blocks of MEMS to realize advances in
sophisticated microsystems and nanomechanical systems.
Nanotechnology research for aerospace applications (Paper Presentation)
Paper 7343-29 of Conference 7343
Authors(s): F. Jack Agee, Alice Chow, Rice Univ. (United States)
Date: Wednesday, 15 April 2009
The scientific community is taking novel approaches to address the high demands
of the aerospace industry. CONTACT (Consortium for Nanomaterials for Aerospace
Commerce and Technology) is a cooperative nanotechnology research program in
Texas that promotes collaboration between universities and accelerates output.
The participants of the program include the Air Force Research Laboratory, five
campuses of the University of Texas (Brownsville, Pan American, Arlington,
Austin, and Dallas), the University of Houston, and Rice University. This paper
provides an overview of the program and projects including the development and
applications of new electrorheological fluids with nano-laden suspensions and
composites.
Optimization of multilayer surface-enhanced Raman scattering (SERS)
immuno-nanosensors via self-assembled monolayer spacers (Paper Presentation)
Paper 7313-11 of Conference 7313
Authors(s): Charles K. Klutse, Honggang Li, Brian M. Cullum, Univ. of Maryland,
Baltimore County (United States)
Date: Thursday, 16 April 2009
Surface enhanced Raman scattering (SERS) is becoming a preferred transduction
method for intracellular nanosensors due to its high sensitivity. Our laboratory
has been assessing the use of multilayers to enhance SERS sensitivity in a
predictable way. This talk will evaluate SERS enhancement of multilayer film
over nanostructures (MULTI-FONs) with self-assembled monolayer (SAMs) spacers.
Monolayers with different chain lengths and tail groups are used as spacers in
order to evaluate the effect of spacer length and chain functionalities on the
SERS enhancement. This talk will also discuss functionalization of the SAM
MULTI-FON with antibodies to develop immuno-nanosensors and the potential use
for intracellular analysis
Nanotechnology enabled sensors and wireless sensing networks (Paper
Presentation)
Paper 7318-32 of Conference 7318
Authors(s): Ray Tsui, Islamshah Amlani, Sal Mastroianni, Motorola, Inc. (United
States); Alvaro Diaz Aguilar, Erica Forzani, Nongjian Tao, Arizona State Univ.
(United States)
Date: Thursday, 16 April 2009
The capabilities of future mobile communication devices will extend beyond
merely transmitting and receiving voice, data, and video information. For
example, first responders such as fire-fighters and emergency workers will wear
environmentally-aware devices that will provide advanced warning of combustible
and toxic gases as well as communicating that information wirelessly to the
Command and Control Center. Similar sensor systems could be employed by
warfighters which would alert to the presence of explosives or chemical and
biological weapons. Novel sensors whose functionality is enhanced via
nanotechnology will play a key role in realizing such systems.
Over the past few years there has been a growing interest in monolithic arrays
of single photon avalanche diodes (SPAD) for spatially resolved detection of
faint ultrafast optical signals.
In order to make SPAD array more and more competitive it is necessary to face
several issues: dark counts, quantum efficiency, crosstalk, timing performance.
These issues will be discussed in the context of two possible approaches to such
a challenge: employing a standard industrial CMOS technology or developing a
dedicated technology. Advances recently attained will be outlined with reference
to both photon counting and Time correlated single photon counting detector
arrays
Nanopatterning of microsensor arrays for pH monitoring (Paper Presentation)
Paper 7318-35 of Conference 7318
Authors(s): Olga Korostynska, Khalil I. Arshak, Arousian Arshak, Edric Gill,
Univ. of Limerick (Ireland)
Date: Friday, 17 April 2009
Novel method of manufacturing micro sensors arrays using BioForce NanoeNablerTM
was successfully employed. These sensors were developed for biomedical
applications, in particular pH monitoring. It is envisaged that findings of this
work would form the basis for miniaturised point-of-care diagnostic system. The
operation of the sensing elements is based on the properties of polymers, which
exhibit a change in their electrical characteristics (such as resistance or
capacitance) on exposure to solutions with different concentrations of pH value.
Carbon-based nanodevices for sensors, actuators, and electronics (Paper
Presentation)
Paper 7318-38 of Conference 7318
Authors(s): Eui-Hyeok Yang, Stevens Institute of Technology (United States)
Date: Friday, 17 April 2009
We are investigating carbon-based nanodevices aimed at developing future
electronic processors with high-performance, bandwidth, and throughput. The
fabrication, assembly and manipulation of carbon nanotubes are investigated for
nanosensors/actuators and nanoelectronics. Further, graphene materials are
fabricated and characterized to investigate its field emission properties for
vacuum electronics and to exploit its differential conductivity for electron
interferometer applications. These devices are deployable in a wide range of
applications such as sensors, detectors, system-on-a-chip, system-in-a-package,
programmable logic controls, energy storage systems and all-electronic systems.
Ultra-nanocrystalline diamond for MEMS and NEMS: opportunities and challenges
(Paper Presentation)
Paper 7318-43 of Conference 7318
Authors(s): Anirudha V. Sumant, Argonne National Lab. (United States)
Date: Friday, 17 April 2009
No description available
Novel nanorod array substrates for high-sensitivity biomolecular sensing (Paper
Presentation)
Paper 7321-3 of Conference 7321
Authors(s): Richard A. Dluhy, Jeremy Driskell, Yiping Zhao, Ralph A. Tripp, The
Univ. of Georgia (United States)
Date: Monday, 13 April 2009
Development of diagnostic methods for rapid and sensitive identification of
viruses and other biomedical pathogens is essential for the advancement of
therapeutic and intervention strategies necessary to protect public health. We
have investigated the use of aligned Ag nanorod arrays, prepared by oblique
angle vapor deposition (OAD), as surface-enhanced Raman scattering (SERS)
substrates for the identification and classification of viral pathogens. The
current talk will address aspects of the fundamental nanostructural design of
metallic nanorod arrays and their influence on SERS enhancement, as well as the
development of a spectroscopic assay for virus detection based on these unique
nanostructured SERS probes. We will also present results of multivariate
statistical analyses on the SERS spectra of different pathogenic species that
indicate that it is possible to identify, differentiate, classify and quantify
biomolecules based on their intrinsic SERS spectra.
Desktop nanofabrication with Dip Pen Nanolithography® (Paper Presentation)
Paper 7318-9 of Conference 7318
Authors(s): Jason R. Haaheim, Omkar A. Nafday, Jae-Won Jang, Paul L. Stiles, Tom
Levesque, NanoInk, Inc. (United States)
Date: Wednesday, 15 April 2009
Dip Pen Nanolithography® (DPN®) is an inherently additive SPM-based technique
which operates under ambient conditions, making it suitable to deposit a wide
range of biological and inorganic materials. These capabilities naturally
suggest a “Desktop Nanofab” concept – a system that allows users to rapidly
create high resolution, scalable nanostructures drawing upon well-characterized
ink and substrate pairings. We will discuss recent efforts towards patterning
nanoscale conductive traces. This flexibility can be realized in a highly
scalable fashion: massively parallel two-dimensional nanopatterning with DPN is
now commercially available via NanoInk’s 2D nano PrintArray™, making DPN a
high-throughput, flexible and versatile method for precision nanoscale pattern
formation.
Electro-optical characterization of individual multiwall carbon nanotubes (Paper
Presentation)
Paper 7318-34 of Conference 7318
Authors(s): Nan Ai, Yao-Tsan Tsai, Eui-Hyeok Yang, Stefan Strauf, Stevens
Institute of Technology (United States)
Date: Friday, 17 April 2009
Carbon nanotubes (CNTs) are a promising material for future high-throughput
nanoelectronic devices operating on a single electron level. We fabricated
field-effect structures based on individual multiwall CNTs bridged between two
gold electrodes on top of a back gate. In the linear response region, a typical
resistance of 10-200 KΩ is measured at 300K. Transistor operation is achieved by
tuning the gate voltage. Measured photocurrents show a wavelength dependence
characterizing the CNT energy levels. We will present detailed measurements of
source-drain, photocurrent, and differential conductance as a function of gate
voltage for CNT structures with various segment lengths.
Nanostructured surfaces for anti-biofouling/anti-microbial applications (Paper
Presentation)
Paper 7318-36 of Conference 7318
Authors(s): Chang-Hwan Choi, Stevens Institute of Technology (United States);
Chang-Jin Kim, Univ. of California, Los Angeles (United States)
Date: Friday, 17 April 2009
No description available
Nanowire microchip biosensor for chem-bio detection (Paper Presentation)
Paper 7312-8 of Conference 7312
Authors(s): A. Dhawan, H. Wang, M. Gerhold, Tuan Vo-Dinh, Duke Univ. (United
States)
Date: Monday, 13 April 2009
No description available
Gold nanoparticle assays: toward single molecule unamplified DNA detection
(Paper Presentation)
Paper 7312-22 of Conference 7312
Authors(s): Remco Verdoold, Dorothee Wasserberg, Felicia Ungureanu, Jan Halamek,
Rob Kooyman, Univ. Twente (Netherlands)
Date: Tuesday, 14 April 2009
Light scattering and absorption properties of gold nanoparticles (GNPs) can be
utilised for the detection of DNA. Binding of molecules to the GNP influences
the local refractive index which can be detected as a red-shift of the GNP’s
extinction maximum. Therefore GNPs are suitable for use as nanoparticle chemical
sensors. Utilizing this method it is possible to detect unamplified DNA from
e.g. pathogens.
Randomly immobilised particles were visualised with a darkfield microscope. For
the detection of single hybridisation events a sandwich assay was developed,
utilizing a second DNA-functionalized GNP. Simultaneous observation of large
numbers of GNPs provides a quantitative assay.
Bacterial SERS sensing using aperiodic metal nanoparticle arrays (Paper
Presentation)
Paper 7312-23 of Conference 7312
Authors(s): Ashwin Gopinath, Sylvanus Y. Lee, Svetlana V. Boriskina, Luca Dal
Negro, Boston Univ. (United States)
Date: Tuesday, 14 April 2009
In this work, Surface-enhanced Raman scattering (SERS) substrates consisting of
periodic and aperiodic arrays of Au nanoparticles were fabricated using e-beam
lithography. The Raman enhancement factors for arrays of different interparticle
separations were experimentally measured utilizing pMA (p-mercapto aniline) as a
SERS reporter and compared with accurate electrodynamical calculations based on
GMT. Results on bacterial sensing using aperiodic arrays will be presented,
showing up to 3x 105 SERS enhancement per bacterium. Our results demonstrate for
the first time that lithographically defined deterministic aperiodic arrays
result in SERS enhancement comparable to traditional SERS substrates obtained by
chemical synthesis.
Long-distance quantum key distribution using superconducting nanowire
single-photon detectors (Paper Presentation)
Paper 7320-12 of Conference 7320
Authors(s): Burm Baek, Sae Woo Nam, National Institute of Standards and
Technology (United States)
Date: Tuesday, 14 April 2009
The recent advances in superconducting nanowire single-photon detector (SSPD)
technology enabled demonstrations of long distance QKDs over an optical fiber
with a decent transmission rate. We will present an overview of our recent
state-of-the-art QKD experiments on an optical fiber using a closed-cycle
cryocooler, multichannel SNSPD system. Together with sophisticated optics,
SNSPDs have extended the secure transmission distance to 100 km or longer in
various platforms and protocols. We will discuss the optimization of the clock
frequency and the gating time for a high transmission rate with the detector
characteristics such as dark count rate, detection efficiency, and timing
jitter.
Photon number resolving detectors at telecom wavelengths based on
superconducting nanowires (Paper Presentation)
Paper 7320-13 of Conference 7320
Authors(s): Andrea Fiore, Francesco Marsili, David Bitauld, Technische Univ.
Eindhoven (Netherlands); Alessandro Gaggero, Roberto Leoni, Francesco Mattioli,
Istituto di Fotonica e Nanotecnologie del CNR (Italy); Aleksander Divochiy,
Alexander A. Korneev, Gregory N. Gol'tsman, Moscow State Pedagogical Univ.
(Russian Federation)
Date: Tuesday, 14 April 2009
We present a novel nanowire-based detector structure, the Parallel Nanowire
Detector (PND), which uses spatial multiplexing on a subwavelength scale to
provide a photon number resolving (PNR) functionality. Counting from 1 to 6
photons was observed, with a photoresponse pulse as short as 660ps, a repetition
rate up to 80 MHz and no multiplication noise. A record sensitivity is obtained
at telecom wavelengths. The PND operation is quantitatively explained by
electrical and optical models. The PND significantly outperforms existing PNR
detectors in terms of simplicity, sensitivity, speed, and multiplication noise.
Ultralow crosstalk multi-element superconducting nanowire single photon (Paper
Presentation)
Paper 7320-14 of Conference 7320
Authors(s): Eric A. Dauler, MIT Lincoln Lab. (United States); Martin J. Stevens,
Burm Baek, National Institute of Standards and Technology (United States);
Richard Molnar, Andrew J. Kerman, MIT Lincoln Lab. (United States); Sae Woo Nam,
Richard P. Mirin, National Institute of Standards and Technology (United
States); Scott Hamliton, MIT Lincoln Lab. (United States); Karl K. Berggren,
Massachusetts Institute of Technology (United States)
Date: Tuesday, 14 April 2009
Multiple detector elements can be fabricated with sub-100-nm gaps between them
and operated independently to detect photons at higher rates, to count multiple
simultaneously-incident photons and to mitigate dead-time effects. The resulting
low level of crosstalk is critical to using the multi-element SNSPDs for certain
applications like intensity correlation measurements, and may also make SNSPDs
an attractive candidate for ultralow-crosstalk photon-counting arrays.
This work was sponsored by the United States Air Force under Air Force Contract
#FA8721-05-C- 0002. Opinions, interpretations, recommendations and conclusions
are those of the authors and are not necessarily endorsed by the United States
Government.
Progress on multipixel superconducting nanowire single-photon detectors for
optical communication (Paper Presentation)
Paper 7320-15 of Conference 7320
Authors(s): Jeffrey A. Stern, David C. Aveline, Bret J. Naylor, William H. Farr,
Jet Propulsion Lab. (United States)
Date: Tuesday, 14 April 2009
Superconducting Nanowire Single Photon Detectors (SNSPDs) have nearly ideal
properties for space-to-ground optical communication at telecommunication
wavelengths (detection efficiency > 50%, jitter < 30 psec, dark counts < 1 kHz
and no after pulsing.) However, the collecting area of a single pixel (typically
100 square microns) is not sufficient; these detectors have a reset time, which
will limit high throughput operation, and cryogenic operation is required. JPL
is currently developing a 16 and 64 pixel SNSPD system, the latter using a
commercial pulse-tube refrigerator. We will present the status of this work, and
discuss the engineering challenges to such an instrument.
Nanoscale electronics (Paper Presentation)
Paper 7343-25 of Conference 7343
Authors(s): Chagaan Baatar, Office of Naval Research (United States)
Date: Wednesday, 15 April 2009
No description available
Exploring assembly at the nanoscale (Paper Presentation)
Paper 7318-2 of Conference 7318
Authors(s): Federico Rosei, Univ. du Québec (Canada)
Date: Wednesday, 15 April 2009
The bottom–up approach is based on the concept of self–assembly of suitable
nanostructures on a substrate. We explore various strategies to control assembly
(both organic and inorganic) at the nanoscale. New experimental tools are
presented to gain fundamental insight into the surface processes that govern
growth, alloying and assembly. We can control the size and luminescence
properties of semiconductor nanostructures. By exploiting inter-molecular
interactions, we create nanoscale patterns with long range order. The general
concept that underpins these studies is the use of surface cues, that guide
molecular units upon adsorption.
EO/IR sensors development using zinc oxide and carbon nanostructures (Paper
Presentation)
Paper 7318-3 of Conference 7318
Authors(s): Ashok K. Sood, Robert A. Richwine, Yash R. Puri, Magnolia Optical
Technologies, Inc. (United States); Dennis L. Polla, Nibir K. Dhar, Defense
Advanced Research Projects Agency (United States); Zhonglin L. Wang, Georgia
Institute of Technology (United States); Priyalal S. Wijewarnasuriya, Army
Research Lab. (United States); Neil Goldsman, Univ. of Maryland, College Park
(United States); Martin B. Soprano, U.S. Army (United States)
Date: Wednesday, 15 April 2009
EO/IR Sensors have been developed for a variety of Military Systems
Applications. These include Visible, SWIR, MWIR and LWIR Nano Sensors. The
conventional SWIR Sensors using InGaAs Focal Plane Array (FPA) can operate in
0.4 - 1.8 micron region. Similarly, MWIR Sensors use InSb and HgCdTe based FPA’s
that are sensitive in 3-5 and 8-14 micron region. DOD investments in the last 10
years have provided the necessary building blocks for the IR Sensors that are
being deployed in the field.
In this paper, we will discuss recent developments and work under way to develop
Next Generation nanostructure based EO/IR detectors and arrays that can
potentially cover UV, Visible and IR regions of interest. The critical
technologies being developed include ZnO nanostructures with wide band gap for
UV detection and Carbon Nanostructures that have shown the feasibility for IR
detection. Experimental results on ZnO based nanostructures demonstrate enhanced
UV sensitivity and path forward for larger arrays. Similarly, recent works on
carbon nanostructures have shown the feasibility of IR detection. Combining the
two technologies in a sensor can provide multispectral capability.
Using dip pen techniques for synthesis of nanostructures (Paper Presentation)
Paper 7318-8 of Conference 7318
Authors(s): Rohit Gargate, Debjyoti Banerjee, Abhay Patil, Texas A&M Univ.
(United States)
Date: Wednesday, 15 April 2009
Using scanning probe lithography techniques we have invented a process for
synthesizing Carbon Nanotubes (CNT) of a single chirality. The CNT synthesis
occurs at ~300-350 ºC where the growth/nucleation is controlled at desired
locations and does not require any process gasses (effectively, the CNT can be
synthesized in vacuum).
In this work, we developed a MEMS platform (Micro Electro Mechanical Systems)
for precisely controlled synthesis of CNT. Parametric studies were performed to
study the effects of catalysts and growth conditions on CNT material properties.
Characterization of InP nanowires grown on non-single-crystal platforms (Paper
Presentation)
Paper 7318-11 of Conference 7318
Authors(s): Drew J. Lohn, Takehiro Onishi, Nobuhiko P. Kobayashi, Univ. of
California, Santa Cruz (United States)
Date: Wednesday, 15 April 2009
InP nanowires were grown by MOCVD on non-single crystal Si and structurally and
optically characterized by scanning electron microscope, x-ray diffraction (XRD),
Raman spectroscopy and cathode luminescence (CL). The XRD data serves as further
evidence of the prior supposition that the two types of nanowires simultaneously
grown
have different crystal structures; wurtzite and zinc-blende. The Raman spectra
appeared
to be those seen in bulk indium phosphide except for subtle peak shift in the TO
and LO
modes. No substantial variation was observed in CL spectra collected along the
growth
axis of the nanowires.
Antibody functionalized magnetic nanowires for cell purification and selective
manipulation (Poster Presentation)
Paper 7318-50 of Conference 7318
Authors(s): Ning Gao, Xiaochuan Yang, Yao-Tsan Tsai, Geh Meh Chu, Hongjun Wang,
Eui-Hyeok Yang, Stevens Institute of Technology (United States)
Date: Thursday, 16 April 2009
In this paper, anti-CD31-functionalized Ni nanowires were used to separate and
selectively manipulate MS-1 endothelial cells from the mixed MS-1 endothelial
and 3T3 fibroblast cells. The purity, viability and yield of target cells were
obtained. This work demonstrates that antibody-functionalized Ni nanowires
provide an effective mean to purify cells. Further studies are required to
uncover the effects on cell morphology and proliferation, and the interaction
between functionalized nanowires and cells.
Fabrication of vertically standing metal nanowire arrays on silicon substrates
using polycarbonate membrane (Poster Presentation)
Paper 7318-57 of Conference 7318
Authors(s): Seongjin Jang, Eui-Hyeok Yang, Stevens Institute of Technology
(United States)
Date: Thursday, 16 April 2009
We propose a new fabrication method to grow vertically aligned nanowire arrays
directly on silicon substrate using commercially available PC. This technique
eliminates the prerequisite procedure to coat the conductive layer on one side
of the template, which is the requirement of the previously reported template
assisted nanowire growth methods. In this study, vertically aligned 6 μm-long
nanowires with a wide range of their diameters were successfully fabricated on
silicon substrate, enabling potential mass production.
Microfabrication of nanowires-based GMR biomedical sensor (Poster Presentation)
Paper 7318-54 of Conference 7318
Authors(s): Ramya Bellamkonda, Mangilal Agarwal, Raja S. Mannam, Daniel Carbo,
James Palmer, Mark DeCoster, Despina Davis, Louisiana Tech Univ. (United States)
Date: Thursday, 16 April 2009
Giant Magnetoresistance (GMR) sensors are multifunctional contactless sensors
since they can be placed on a single chip with all needed electrical circuitry.
This study focuses on GMR based integrated microfluidic sensor device, which can
detect toxicants or cells by utilizing magnetic field and electrical voltage.
The results obtained from developed nanowire based GMR device using four
different control solutions: 1) polystyrene superparamagnetic beads, 2)
commercially available magnetic Dynabeads, 3) secondary antibodies bound to the
Dynabeads and 4) Jurkat cells bound to the Dynabeads is presented.
Nanomaterials and nanostructures research for integrated adaptive multimodal
sensing (Keynote Presentation) (Keynote)
Paper 7318-33 of Conference 7318
Presenter(s): Kitt C. Reinhardt, Air Force Office of Scientific Research (United
States)
Date: Friday, 17 April 2009
An overview of AFOSR sponsored research in novel integrated multi-mode
(intensity, wavelength, polarization, phase, etc.) sensor concepts will be
presented. Research approach and progress achieved toward various innovative
concepts for near-real time tuning of sense-mode ‘select’ and pixel location
‘read’ functions will be presented; including very recent developments in
transparent electronics/interconnects and lattice-mismatched absorber materials
enabling for vertically-integrated multi-modal pixel concepts. Of special
interest is recent progress in absorption band-edge engineering and dynamic
tuning resulting from synthesis of innovative homogeneous and heterogeneous
structures based on combinations of one or more 0D, 1D, and 2D quantum and nano-based
assemblies and interactions.
Nanostructures for stray light suppression (Paper Presentation)
Paper 7318-40 of Conference 7318
Authors(s): John G. Hagopian, James J. Butler, Stephanie A. Getty, Donald E.
Jennings, Mary J. Li, Patrick A. Roman, June L. Tveekrem, Manuel A. Quijada,
NASA Goddard Space Flight Ctr. (United States)
Date: Friday, 17 April 2009
Observations of the Earth are extremely challenging; it’s large angular extent
floods scientific instruments with high flux within and adjacent to the desired
field of view. Stray light is controlled by utilizing low reflectance surface
treatments, using baffles and stops to limit background noise. Recent work by
GSFC researchers has discovered that nanostructures are exceptionally good
absorbers, with potential to provide order-of-magnitude improvement over current
surface treatments and orders of magnitude system stray light control.
Development of this technology will provide numerous benefits including: a.)
simplification of instrument stray light controls b.) increasing observational
efficiencies c.) enabling low-noise observations.
Fabrication of a nanoscale electric field sensor (Paper Presentation)
Paper 7318-41 of Conference 7318
Authors(s): Yun T. Zheng, Todd T. King, Daniel S. Stewart, Stephanie A. Getty,
NASA Goddard Space Flight Ctr. (United States)
Date: Friday, 17 April 2009
Direct detection of biomarkers, nanoparticles, bacteria, and virus in blood
and other biological samples (Paper Presentation)
Paper 7312-5 of Conference 7312
Authors(s): Michael J. Heller, Univ. of California, San Diego (United States)
Date: Monday, 13 April 2009
In many research and diagnostic applications it is a significant challenge to
directly isolate and identify rare cells, bacteria, virus, nanoparticles and
other important biomarkers directly in blood and plasma. Dielectrophoresis (DEP)
offers a particularly attractive mechanism for high resolution separation of
cells and nanoparticles. Unfortunately, DEP requires considerable dilution of
the sample making it impractical for diagnostic applications. We have now
clearly demonstrated the DEP separation and detection of nanoparticles and DNA
directly in un-diluted whole blood. This DEP detection technology is now being
used for the direct detection of bacteria and virus in blood.
Gold nanoparticles for immunosensing using darkfield imaging (Paper
Presentation)
Paper 7312-6 of Conference 7312
Authors(s): Dorothee Wasserberg, Felicia Ungureanu, Jan Halamek, Vinod
Subramaniam, Rob Kooyman, Univ. Twente (Netherlands)
Date: Monday, 13 April 2009
The extinction spectra of gold nanoparticles (AuNPs) change upon changes in the
refractive index of the material surrounding them. Thus, changes in the
extinction spectra of AuNPs are determined by the composition of the surrounding
material providing a method to study binding events on AuNPs by observing this
‘change of colour’. We have used this effect to construct an immunosensor using
darkfield imaging.
Antibodies conjugated to AuNPs could be immobilised in micro flow cells and
studied using darkfield imaging. Upon immunoreaction a change of colour could be
observed proving the viability of this setup as nanoparticle-based immunosensor.
Detecting Escherichia coli strains using magnetically loaded fluorescence
labeled polymeric nanoparticles (Paper Presentation)
Paper 7315-1 of Conference 7315
Authors(s): Erhan Piskin, Hacettepe Üniv. (Turkey)
Date: Tuesday, 14 April 2009
Development of novel detection systems for pathogenic microorganisms is a very
critical issue worldwide and attracting an increasing attention. This study
attempts to develop a simple preconcentration and diagnostic test kit for
detection of E. coli bacteria especially in food products which is based on
magnetically loaded polymeric nanoparticles. These nanoparticles were prepared
at three step process. First, “magnetite” nanoparticles were produced by a
precipitation technique from the iron salts and were coated with an acrylate
based polymer layer. In the final step D-mannose molecules (a pseudo-specific
bioligand against the surface mannose receptors of E. coli strands) were
covalently immobilized on the nanoparticles, which were also
fluorescence-labeled. Interactions were detected by using a Fluorescence
microscopy.
Advances in micro-nano technologies for imaging sensors (Keynote Presentation)
(Keynote)
Paper 7318-1 of Conference 7318
Presenter(s): Nibir K. Dhar, Army Research Lab. (United States)
Date: Wednesday, 15 April 2009
Please see below
Nanotube MEMS: developing extreme nanoscale devices (Paper Presentation)
Paper 7318-5 of Conference 7318
Authors(s): Slava V. Rotkin, Lehigh Univ. (United States)
Date: Wednesday, 15 April 2009
Far from reaching its limits, MEMS technology proved itself in various
applications, ranging from car acceleration and pressure sensors to space
telescope shutters. Nowadays MEMS devices approach nanometer scale, promising
even larger versatility, including hybrid THz-electronics, low-power memories
and sensors with record sensitivity.
NEMS engineering enters, however, a new territory, full of surprises and
paradoxes. The talk gives vignettes of physics of NEMS devices, both existing
and theoretically proposed, utilizing nanotube materials. Natural size of a
single nanotube is small enough so the quantum effects develop. We will review
such novel effects which differentiate Nanotube-NEMS from their classical MEMS
counterpart.
Reviews of nano-manipulators (Paper Presentation)
Paper 7343-28 of Conference 7343
Authors(s): Toshio Fukuda, Nagoya Univ. (Japan)
Date: Wednesday, 15 April 2009
No description available
Probing the interaction of human plasma proteins and nanoparticles (Paper
Presentation)
Paper 7313-2 of Conference 7313
Authors(s): Silvia H. Lacerda, National Institute of Standards and Technology
(United States)
Date: Thursday, 16 April 2009
Protein adsorption plays a major role in the biocompatibility properties of any
material. When nanoparticles enter a biological fluid, they associate to plasma
proteins, which define their biological activity. NPs interaction with proteins
can undergo a conformational change and formation of aggregates. That has an
effect on the transport and accumulation of NPs on tissues and cells, to change
the protein structure and function and be related to their toxicity. In this
work we characterize the association of gold nanoparticles in the range with
proteins found in the human blood plasma.
Multifunctional nanocarriers based on dendronized gold nanoparticles (Paper
Presentation)
Paper 7313-3 of Conference 7313
Authors(s): Marie-Christine Daniel, Margaret Grow, Maria Bednarek, Cesar Baeta,
Univ. of Maryland, Baltimore County (United States)
Date: Thursday, 16 April 2009
Multifunctional nanocarriers present important advantages for application in
cancer research. Among them, due of their nanometric size, they can passively
target the tumor tissues through the enhanced permeability and retention (EPR)
effect. Also, their ability to acquire in vivo longevity enables them to reach
the tumor at higher concentration. For diagnosis purpose of pancreatic cancer,
the preparation of dendronized gold nanoparticles combining targeting moieties
and imaging agents were performed. The chosen targeting ligand is transferrin
because of the overexpression of transferrin receptor on the pancreatic cancer
cells. And the imaging agent used is a magnetic resonance (MR) contrast agent.
Interaction of gold nanoparticles with Hb and BSA (Paper Presentation)
Paper 7313-15 of Conference 7313
Authors(s): Poorani G. Gananathan, Sivabalan Shanmugam, Aruna Prakasa Rao,
Singaravelu Ganesan, Anna Univ. (India)
Date: Thursday, 16 April 2009
The aim of this study was to evaluate the nature of interaction of Hemoglobin (Hb)
and Bovine Serum Albumin (BSA) in the presence of metallic nanoparticles. Gold
nanospheres of various size were prepared by reduction technique and the
particles formation was confirmed with UV-Visible absorption spectroscopy. The
size of the particle was calculated theoretically based on absorption spectra.
Interaction studies for BSA and Hb were carried out and characterized using
optical spectroscopic techniques. In absorption studies, red shift in absorption
maxima of GNP is observed which is due to folding of proteins. Concentration
dependant quenching of fluorescence in fluorescing amino acids of protein
molecules and enhancement of fluorescence in nanoparticles were observed. The
absorption and fluorescence studies reveal that the Au nanospheres enhance
protein folding in biomolecules and it is an effective tool for biosensor
applications.
Combining plasmonics and MEMS/NEMS for higher performance sensor systems (Paper
Presentation)
Paper 7318-6 of Conference 7318
Authors(s): Aykutlu Dana, Bilkent Univ. (Turkey)
Date: Wednesday, 15 April 2009
Well defined periodic or quasi-periodic structures consisting of metal and
dielectric components may be designed to exhibit plasmon resonances with high
quality factors. Such resonances are very sensitive to environmental
optical properties. In this study, we investigate other means of modulating
plasmon resonances, where resonances are coupled to mechanical properties of
micro and nanoelectromechanical
devices. Various opto-electro-mechanical devices featuring micron and submicron
features are theoretically and experimentally studied where modulation of
optical signals due to plasmonic effects are used as a readout mechanism.
Results suggest that plasmon resonances present a feasable and sensitive readout
mechanism for micro and nanoelectromechanical systems, and can be combined with
more conventional plasmon resonance based detection for superior sensing.
Protein nanoarray made by size-dependent self-assembly for detection of mouse
immunoglobulin G and octamer-4 (Paper Presentation)
Paper 7313-5 of Conference 7313
Authors(s): Phat L. Tran, Tremaine B. Powell, Keesung Kim, Jeong-Yeol Yoon, The
Univ. of Arizona (United States)
Date: Thursday, 16 April 2009
A protein nanoarray is created when submicro and nano beads, varying in their
size and each conjugated with different proteins, self-assemble to specific
locations depending on the diameter matching the surface electron beam patterns
created. Protein binding is confirmed from the fluorescence attenuation and FRET
upon antigen-antibody binding on the bead surface. We tested this system for
mouse immunoglobulin G (positive control) and Octamer-4 (a transcription factor
from embryonic stem cells). This method, called size-dependent self-assembly,
allows control of the location of each type of bead, and thus, control of the
location of multiple proteins.
Integrated amplification and passivation nanolayers for ultra-high-sensitivity
photodetector arrays: application for LIBS and Raman spectroscopy (Paper
Presentation)
Paper 7304-38 of Conference 7304
Authors(s): Jie Yao, B&W Tek, Inc. (United States); Patrick J. Gardner, Western
Carolina Univ. (United States)
Date: Wednesday, 15 April 2009
No description available
Theoretical and experimental development of label-free biosensors based on
localized plasmon resonances on nanohole and nanopillar arrays (Paper
Presentation)
Paper 7322-2 of Conference 7322
Authors(s): Radislav A. Potyrailo, GE Global Research (United States)
Date: Thursday, 16 April 2009
In this work, we present results on theoretical and experimental development of
label-free biosensors based on localized surface plasmon resonance (LSPR)
detection. Transducers based on LSPR have several advantages over conventional
Kretschmann configurations that include simple transmission measurement system
design, operation with an un-polarized light source, and a simple spectral
detection of color shift of the LSPR response. For highly sensitive plasmonic
sensing, we employ nanohole and nanopillar arrays integrated into our fluidic
components.
Portable, instantaneous, and ultrasensitive detection of micro-organisms based
on interferometry and lab-on-a-chip nanotechnology (Paper Presentation)
Paper 7306A-20 of Conference 7306A
Authors(s): Aurel Ymeti, Ostendum and Univ. Twente (Netherlands)
Date: Wednesday, 15 April 2009
Future viral outbreaks are a major threat to societal and economic development
throughout the world. A rapid, sensitive, and easy-to-use test for viral
infections is essential to prevent and to control such viral pandemics.
We have developed a rapid, ultrasensitive sensor that could be used in a
handheld device to detect various viruses and measure their concentration. The
sensor’s detection principle can be extended to any biological target such as
viruses, bacteria and proteins for which there are specific antibodies. The
nature of the sensor enables multiplexed detection of several pathogenic species
at the same time.
Aligned nanotubes in 3D nanoscale architectures formed using high-throughput
manufacturable processes for electronics and sensing applications (Paper
Presentation)
Paper 7318-10 of Conference 7318
Authors(s): Anupama B. Kaul, Krikor Megerian, Paul A. von Allmen, Richard L.
Baron, Jet Propulsion Lab. (United States)
Date: Wednesday, 15 April 2009
Despite their unique and promising materials properties, the main impediment of
carbon nanotubes for device applications has been the inability to control their
orientation, chirality, or implementing manufacturable processes, especially
where just single tubes are desired. We have developed manufacturable approaches
to form single, vertically aligned, metallic carbon nanotubes, where the tubes
are centered precisely, and placed within a few hundred nm of 1-1.5 m deep
trenches. Such scalable, high throughput top down fabrication techniques,
integrated with the bottom up synthesis of tubes, should accelerate the
development of PECVD tubes for a wide variety of applications in electronics and
sensing.
Nanocrystalline Cu-doped zirconia film-coated long-period fiber grating for CO
monitoring at high temperature (Paper Presentation)
Paper 7322-11 of Conference 7322
Authors(s): Xiling Tang, Jian Zhang, Junhang Dong, Univ. of Cincinnati (United
States); Tao Wei, Hai Xiao, Missouri Univ. of Science and Technology (United
States)
Date: Thursday, 16 April 2009
Physically and functionally integrating materials with special properties into
miniaturized single device is one of the central themes of intelligent
technology development. The integrated devices can either offer enhanced
functionality or realize the unique capabilities of the constituting materials
that otherwise cannot be accessed by the individual material alone. Recently, we
have successfully integrated various nano-structured inorganic thin films with
long-period fiber grating (LPFG) as fiber optic sensors for gas measurement in
different conditions. Here we report the development of Cu-doped zirconia (CDZ)
nanocrystalline thin-film coated LPFG sensors for in-situ high temperature CO
monitoring.
Tribological issues critical to MEMS and NEMS performance: studies of ultra-nanocrystalline
diamond with other MEMS materials (Paper Presentation)
Paper 7318-44 of Conference 7318
Authors(s): Robert W. Carpick, Univ. of Pennsylvania (United States)
Date: Friday, 17 April 2009
No description available
Fundamentals and application of materials integration for low-power
piezoelectrically actuated ultra-nanocrystalline diamond MEMS/NEMS (Paper
Presentation)
Paper 7318-47 of Conference 7318
Authors(s): Orlando Auciello, Argonne National Lab. (United States)
Date: Friday, 17 April 2009
No description available
Bio-inspired synthesis and laser processing of nanostructured barium titanate
thin films: implications for uncooled IR sensor development (Paper Presentation)
Paper 7321-2 of Conference 7321
Authors(s): Frank E. Livingston, The Aerospace Corp. (United States); Wendy L.
Sarney, Army Research Lab. (United States); Andrea R. Tao, Daniel E. Morse,
Univ. of California, Santa Barbara (United States)
Date: Monday, 13 April 2009
The Army requires passive uncooled IR sensors for use in numerous vehicle and
weapons platforms, including driver vision enhancement (DVE), rifle sights,
seeker munitions, and unattended ground sensors (UGSs) and unattended aerial
vehicles (UAVs). Recent advances in bio-inspired/biomimetic nanomaterials
synthesis, laser material processing, and sensor design and performance testing,
offer the opportunity to create uncooled IR detector focal-plane arrays with
improved sensitivity, low thermal mass, and fast response times, along with
amenability to low cost, rapid prototype manufacture. We are exploring the use
of digitally-scripted, laser direct-write techniques, in conjunction with the
kinetically controlled catalytic process for the growth of nanostructured
multimetallic perovskites, to develop a novel approach to the fabrication of
precision patterned 2-D focal-plane arrays of pyroelectric perovskite-based
materials.
Multiwalled carbon nanotubes modified with ferrocene-amino acid derivatives as
electrochemical sensors for chemical warfare agent mimics (Paper Presentation)
Paper 7304-28 of Conference 7304
Authors(s): Yizh Xiao, The Univ. of Western Ontario (Canada); Michael W. Petryk,
Defence Research and Development Canada (Canada); Heinz-Bernhard Kraatz, The
Univ. of Western Ontario (Canada)
Date: Wednesday, 15 April 2009
The interest in the detection of chemical warfare agents (CWAs) has been growing
with the rise in the concern over the use of such compounds in criminal
terrorist attacks. They are easily produced and often have extreme toxicity.
This makes it necessary to have rapid, reliable and affordable methods for the
determination of CWAs and their related degradation products. Ideally, such a
detection system will possess a high sensitivity and reproducibility, have a
high selectivity to specific agents, will require little or no sample
preparation, and will be suitable for field operations in terms of rugged
design, thermal stability, low sensitivity to common contaminants, modest power
requirements, and low reliance upon consumables. In our group, we focus on the
electrochemical detection of chemical warfare agent (CWA) mimics using modified
multi-walled carbon nanotubes (MWCNTs) supported on indium tin oxide (ITO)
surfaces. Briefly, MWCNTs are covalently or non-covalently modified with a
number of redox-active ferrocene (Fc)-amino acid conjugates. The Fc-conjugate
acts as redox-active component that is sensitive to intermolecular interactions.
Upon expose to CWA mimics the electrical properties of the MWCNTs and the Fc
group were affected significantly. Alternating current voltammetry (ACV) and
capacitance-based detection offered large dynamic ranges for the detection of
methylphosphonic acid (MPA), diethyl cyanophosphonate (DECP),
ethylmethylphosphonate (EMP) and pinacolyl methylphosphonate (PMP) in water. The
electrical measurements showed dramatic changes upon the electrostatic affinity
between the negatively charged CWA mimics and the positively charged ferrocene-amino
acid conjugates immobilized on MWCNTs. Electrochemical sensing with MWCNTs is
shown to be a promising analytical tool for the trace-level detection of
water-soluble CWA mimics.
Integration of a carbon nanotube field emission electron gun for a miniaturized
time-of-flight mass spectrometer (Paper Presentation)
Paper 7318-42 of Conference 7318
Authors(s): Stephanie A. Getty, Mary J. Li, Nicholas P. Costen, Larry A. Hess,
Todd T. King, Patrick A. Roman, William Brinckerhoff, Paul R. Mahaffy, NASA
Goddard Space Flight Ctr. (United States)
Date: Friday, 17 April 2009
A carbon nanotube (CNT) field emission electron gun has been integrated as an
electron impact ionization source for a miniaturized time-of-flight mass
spectrometer (TOF-MS). The cathode consists of a patterned array of CNT towers
grown by catalyst-assisted thermal chemical vapor deposition. An extraction grid
is precisely integrated in close proximity to the emitter tips, and an anode is
located at the output to monitor the ionization beam current. Objectives of the
work include reduced extraction voltage during operation and enhanced current
transmission. Performance of the CNT electron gun will be reported, and
implications for planetary science will be discussed.
Photonic bandgap fiber with immobilized Ag nanoparticles in the core-hole
channel for SERS-based measurements of aqueous solutions (Paper Presentation)
Paper 7316-42 of Conference 7316
Authors(s): Yun Han, Maung K. Khaing Oo, Svetlana A. Sukhishvili, Henry H. Du,
Stevens Institute of Technology (United States)
Date: Friday, 17 April 2009
We report an investigation of immobilization of Ag nanoparticles inside the
core-hole structure of a photonic bandgap fiber (PBF) to make a robust platform
for sensing and detection of ultra-trace analytes in aqueous solutions by means
of surface-enhanced Raman scattering (SERS). For the first time, SERS signal in
the fiber transmission mode was recorded using Raman imaging system, which
reveals propagation mode of signals in Ag nanoparticle modified liquid core PCF
(LC-PCF). Sensitive and reproducible measurements of 10-7 M were achieved for
both thiocyanate and R6G in water from the SERS active LC-PCF.
Development of a bionanoprobe sensing concept employing molecular recognition
and multifunctional transduction (Paper Presentation)
Paper 7304-3 of Conference 7304
Authors(s): Dimitra N. Stratis-Cullum, Army Research Lab. (United States);
Nicole Whitten, Univ. of Maryland, Baltimore County (United States) and Army
Research Lab. (United States); Mikella E. Hankus, Army Research Lab. (United
States); Brian M. Cullum, Univ. of Maryland, Baltimore County (United States);
Paul M. Pellegrino, Army Research Lab. (United States)
Date: Tuesday, 14 April 2009
In this work, we are exploring enhanced selectivity through targeted recognition
at the molecular level, in combination with SERS and multifunctional
spectroscopic transduction. Water-stable SERS substrates which are modified with
nucleic acid aptamer functionality are designed to specifically recognize a
target threat or stimulant material. We will report on development progress
towards a hybrid molecular recognition with SERS/Fluorescence nanoprobe system
including the optimization, fabrication, and spectroscopic analysis of
water-stable substrate. The feasibility of this single-step switching
architecture for hazard material detection will also be discussed.
Development of a THz heterodyne receiver with quantum cascade laser and hot
electron bolometer mixer for standoff detection of explosive material (Paper
Presentation)
Paper 7311-3 of Conference 7311
Authors(s): Heiko Richter, Alexei D. Semenov, Heinz-Wilhelm Hübers, Sergey
Pavlov, Deutsches Zentrum für Luft- und Raumfahrt e.V. (Germany); Lukas Mahler,
Alessandro Tredicucci, Scuola Normale Superiore di Pisa (Italy); Harvey E. Beere,
David A. Ritchie, Univ. of Cambridge (United Kingdom); Michele Ortolani,
Istituto di Fotonica e Nanotecnologie del CNR (Italy); Ulrich Schade, BESSY GmbH
(Germany); Konstantin S. Ilin, Michael Siegel, Univ. Karlsruhe (Germany)
Date: Tuesday, 14 April 2009
The terahertz (THz) portion of the electromagnetic spectrum provides specific
spectroscopic information for substance identification. It has been shown that
the spectral features of explosive materials might be used for detection and
identification at stand-off distances. We will report on the development of a
THz spectrometer for explosive detection and identification. The system is based
on THz quantum cascade lasers working at different frequencies. These are used
for illumination of the object under test. The reflected and backscattered
radiation from the object under test is detected with a sensitive heterodyne
receiver. The concept of the system and first results will be presented.
Terahertz reflectance spectra of pure explosive materials at normal and oblique
incidence (Poster Presentation)
Paper 7311-29 of Conference 7311
Authors(s): Michele Ortolani, Istituto di Fotonica e Nanotecnologie del CNR
(Italy) and BESSY GmbH (Germany); Ulrich Schade, BESSY GmbH (Germany); Jongseok
Lee, BESSY GmbH (Germany) and ERATO-MF (Japan); Heinz-Wilhelm Hübers, Heiko
Richter, Deutsches Zentrum für Luft- und Raumfahrt e.V. (Germany)
Date: Tuesday, 14 April 2009
We studied the terahertz reflectance spectra of explosives at both
quasinormal and oblique incidence by Fourier-transform spectroscopy. The optical
constants of
the explosives RDX and PETN were determined from the reflectance spectra of pure
optically flat pellets and clear spectral signatures were found in the 0.5–8 THz
range. In the case of a realistic surface roughness of several tens of microns,
the observation of the spectral signatures at quasinormal incidence is hindered
by the specular reflectance roll-off at terahertz frequencies. On increasing the
angle of incidence, the roll-off occurred at higher frequency and the surface
roughness was optically measured.
Novel configuration coupling surface plasmon resonance and electrokinetic
separations for quantitative monitoring of biomolecules (Paper Presentation)
Paper 7313-16 of Conference 7313
Authors(s): Karl S. Booksh, Michael R. Malone, Univ. of Delaware (United States)
Date: Thursday, 16 April 2009
A flexible sensor platform combining label free detection through localized
surface plasmon resonance imaging and electro kinetic based separations of
complex biofluids is under development. The combination of these two techniques
will greatly enhance the capabilities of remote biosensing for clinical
analysis. The separation of medically relevant proteins from the milieu of
different biofliuds and the potential for pre concentration of analytes through
electro focusing methods will increase the accuracy of measurement made through
traditional SPR methodologies. The label free detection of Surface Plasmon
Resonance eliminates the need for sample preparation. The hybrid platform
involves Imaging spectra from Localized Surface Plasmon Resonance effects on
Nanoparticles embedded in the sample channels. Nanoparticles with tetrahedron
and spherical geometries have been characterized.
Multichannel surface-enhanced Raman scattering probe based on photonic crystal
fiber (Paper Presentation)
Paper 7316-39 of Conference 7316
Authors(s): He Yan, Jie Liu, Zhonghuan Zhang, Mingshan Li, Tsinghua Univ.
(China); Lantian Hou, Yanshan Univ. (China); Changxi Yang, Tsinghua Univ.
(China)
Date: Friday, 17 April 2009
A multi-channel surface-enhanced Raman scattering (SERS) probe based on a
multi-core photonic crystal fiber (MCPCF) is investigated. The MCPCF contains
seven hollow core PCFs those can guide light respectively, providing seven
channels for sensing. Analyte solution mixed with the silver nanoparticles
enters each core via the capillary effect. The excitation light transmitting in
each hollow core can interact with the analyte and the silver nanoparticles in
the holes directly which promises higher efficiency of light usage. Accurate
results could be achieved with minimal instability from the multi-data of the
analyte. The experimental results show that our probe has a good performance on
Rhodamine 6G molecules.
High-strength transparent spinel with fine, unimodal grain size (Paper
Presentation)
Paper 7302-16 of Conference 7302
Authors(s): Sean M. Sweeney, Milivoj K. Brun, Timothy J. Yosenick, Anteneh
Kebbede, Mohan Manoharan, GE Global Research (United States); Lisa P. Franks,
U.S. Army Tank-Automotive Research, Development and Engineering Ctr. (United
States)
Date: Wednesday, 15 April 2009
Spinel (MgAl2O4) is a good candidate material for transparent armor and IR
window applications. Traditionally, transparent spinel has suffered from poor
strength and difficult polishing owing to its large, bimodal grain structure.
Starting from a spinel nanopowder, spinel ceramics with a grain size of less
than 2 microns have been made with better than 80% in-line transmittance at 632
nm wavelength for 3/8” thick samples. A ring-on-ring test has been used to
measure biaxial flexural strength on samples machined to 0.8 mm thickness. The
average strength was found to exceed 480 MPa.
Multispectral EO/IR sensor model for evaluating UV, visible, SWIR, MWIR and LWIR
system performance (Paper Presentation)
Paper 7300-17 of Conference 7300
Authors(s): Ashok K. Sood, Robert A. Richwine, Yash R. Puri, Magnolia Optical
Technologies, Inc. (United States); Nibir K. Dhar, Dennis L. Polla, Defense
Advanced Research Projects Agency (United States); Priyalal S. Wijewarnasuriya,
Army Research Lab. (United States)
Date: Wednesday, 15 April 2009
Next Generation EO/IR Sensors using Nanostructures are being developed for a
variety of Defense Applications. In addition, large area IRFPA’s are being
developed on low cost substrates. In this paper, we will discuss the
capabilities of a EO/IR Sensor Model to provide a robust means for comparing
performance of infrared FPA’s and Sensors that can operate in the visible and
infrared spectral bands that coincide with the atmospheric windows – UV,
Visible-NIR (0.4-1.8), SWIR (2.0-2.5), MWIR (3-5), and LWIR (8-14).
The model will be able to predict sensor performance and also functions as an
assessment tool for single-color and for multi-color imaging. The detector model
can also characterize ZnO, Si, SiGe, InGaAs, InSb, HgCdTe and Nanostructure
based Sensors. The model can predict performance by also placing the specific
FPA into an optical system, evaluates system performance (NEI, NETD, MRTD, and
SNR). This model has been used as a tool for predicting performance of
state-of-the-art detector arrays and nanostructure arrays under development.
Results of the analysis will be presented for various targets for each of the
focal plane technologies for a variety of missions.
Hand-held, highly reliable, selective, direct, and reagentless detection (Paper
Presentation)
Paper 7304-34 of Conference 7304
Authors(s): Melik C. Demirel, The Pennsylvania State Univ. (United States)
Date: Wednesday, 15 April 2009
We developed a wireless, highly accurate, handheld, real time sensor for
chemical, biological, and explosive (CBE) detection. The new handheld laser
technology provides significant advantages over traditional methods based on the
nanostructured detection-chips using polymer surface coatings technology and a
handheld Raman spectroscopy analyzer. Our chip and hand-held sensor provide
highly sensitive, reproducible and uniform detections of CBE agents for civilian
and military security problems. Our technology reduces the time (<10 sec) and
cost (<$5/sample) for CBE detection with potential improvements in detection
specificity and sensitivity at low laser powers (<1mW).
Bead-based assays for biodetection: from flow-cytometry to microfluidics (Paper
Presentation)
Paper 7306A-19 of Conference 7306A
Authors(s): Richard M. Ozanich, Kate Antolick, Cindy Bruckner-Lea, Kyle J.
Bunch, Brian Dockendorff, Jay W. Grate, Cynthia Warner, Marvin G. Warner,
Pacific Northwest National Lab. (United States)
Date: Wednesday, 15 April 2009
The potential for the use of biological agents by terrorists is a real threat.
Two approaches to detection of biological species will be described: 1) The use
of microbead arrays for multiplexed flow cytometry detection of chemokines and
botulinum neurotoxin simulant, and 2) a microfluidic platform for capture and
separation of different size functionalized superparamagnetic nanoparticles
followed by on-chip fluorescence detection of the sandwich complex. Unique
methods and automated fluidic systems for trapping functionalized microbeads
that allow samples and assay reagents to be efficiently perfused over a
micro-column of beads, resulting in faster and more sensitive assays will be
described. Automated fluidic assays were compared to “batch” assays conducted in
microfuge tubes for human chemokines and botulinum neurotoxin Type A heavy chain
fragment (BoNT/A-HC). The automated fluidic approach resulted in up to five-fold
improvements in assay sensitivity/speed. Preliminary results also indicate the
fluidic system can preconcentrate trace target analytes from large volume
samples. The automated fluidic platform can readily be adapted to other target
analytes by simply using different functionalized microbeads and reagents. In
addition, this platform can be integrated with various types of detectors. The
goal of the microfluidic-based approach is to achieve rapid (<20 minutes),
multiplexed (> 3 bioagents) detection using a simple and low-cost, integrated
microfluidic/optical detection platform. Initial work has demonstrated
separation and detection of two different fluorescently-labeled magnetic
nanoparticles (NPs) in a microfluidic device. An initial microfluidic device was
tested using a fluorescent sandwich immunoassay. Using fiber-optic guided
laser-induced fluorescence, assay detection limits were shown to be in the 100’s
of picomolar range (10’s of micrograms per liter) for BoNT/A-HC without any
optimization of the microfluidic device or optical detection approach.
Significant improvements in limits of detection are expected. Video taping NP
capture and release was used to improve understanding of the process and
revealed interesting NP behavior (i.e., NP release results in uniform and
complete dissolution/deaggregation thought to be the result of rapid repulsion
of NPs that were tightly captured together in a microfluidic channel). The
potential to exploit this unique behavior will be investigated in future
research.
Colour camera: a new detection method for protein binding (Paper Presentation)
Paper 7312-4 of Conference 7312
Authors(s): Felicia Ungureanu, Jan Halamek, Remco Verdoold, Rob Kooyman, Univ.
Twente (Netherlands)
Date: Monday, 13 April 2009
Here we report on a new detection method of binding events of analytes to
functionalized gold nanoparticle using a standard colour camera attached to a
darkfield microscopy setup. This setup is capable of parallel detection of the
spectral shifts of thousands of 60 nm antibody-functionalized gold spheres as a
result of binding events of protein analyte molecules. The results obtained with
the colour camera compare well with the scatter microspectroscopy studies. This
setup can be the base for multiplexing and quantification.
Modified ZSM-5 zeolite film-integrated fiber optic sensors for ammonia detection
(Paper Presentation)
Paper 7312-11 of Conference 7312
Authors(s): Xiling Tang, Zhong Tang, Seok-Jhin Kim, Junhang Dong, Univ. of
Cincinnati (United States)
Date: Monday, 13 April 2009
Recently, we have successfully integrated the crystalline nanoporous zeolite
thin films with various structured-optical fibers to construct fiber optic
sensors for chemical detections. Here we report the development of surface
modified ZSM-5 zeolite crystal thin-film coated long-period fiber grating (LPFG)
sensors for in-situ detection of ammonia (NH3) in complex gas mixtures. The
sensor was fabricated by growing MFI-type zeolite thin film (i.e. ZSM-5 with Si/Al
ratio of 15 ~ 20) on the optical fiber grating by in situ hydrothermal
crystallization. The sensor measures ammonia concentration by monitoring the
molecular adsorption-induced shift of LPFG resonant wavelength (R) in near
infrared (IR) region.
Sub-millimeter resolution laser ranging at 9.3 kilometers using temporally
stretched, frequency chirped pulses from a mode locked laser (Paper
Presentation)
Paper 7339-16 of Conference 7339
Authors(s): Mohammad Umar Piracha, Dat Nguyen, College of Optics & Photonics,
Univ. of Central Florida (United States); Tolga Yilmaz, Raydiance, Inc. (United
States); Dimitrios Mandridis, College of Optics & Photonics, Univ. of Central
Florida (United States); David Gaudiosi, Raydiance, Inc. (United States); Peter
J. Delfyett, Jr., College of Optics & Photonics, Univ. of Central Florida
(United States)
Date: Tuesday, 14 April 2009
A chirped fiber Bragg grating was used to temporally stretch picosecond pulses
from a 20MHz passively mode locked fiber laser to a few nanoseconds duration.
This allows the generation of stretched pulses of higher output power if the
temporal duration of the input pulse is longer than the storage time of the
external amplifier. Moreover, non-linear effects can also be avoided. This
technique is suitable for ladar applications where pulses with large powers are
required for sufficient received signal detection. A fiber based
interferometeric arrangement was used for interfering the return signal from the
target with the reference signal to realize a coherent heterodyne detection
scheme. In the RF domain, the detected heterodyned frequency shifts as the
object distance is changed. Sub-millimeter resolution was observed with 9.3km of
fiber delay.
Development of optical antenna-coupled Si CMOS-based detector at 30 THz (Paper
Presentation)
Paper 7311-11 of Conference 7311
Authors(s): JeongSun S. Moon, HRL Labs., LLC (United States); Kyung-Ah Son,
Goutam Chattopadhyay, David Z. Ting, Jet Propulsion Lab. (United States)
Date: Tuesday, 14 April 2009
In this paper, we will present a world-first Si CMOS-based antenna-coupled
detector, designed for 10 m (30 THz) photon detection. The antenna-coupled Si
LWIR detectors are fabricated with a highly-efficient antenna design, and
integrated with nanoscale Si MOS diodes. Electromagnetic simulation of the
antenna shows an efficient coupling to 30 THz radiation. Measured LWIR detection
at room temperature will be presented and its mechanism will be discussed.
Chemical detection using flexible metal-organic frameworks (Paper Presentation)
Paper 7318-7 of Conference 7318
Authors(s): Mark D. Allendorf, Ronald J. T. Houk, A. Alec Talin, Sandia National
Labs. (United States); Leanne Andruszkiewicz, Peter J. Hesketh, Georgia
Institute of Technology (United States)
Date: Wednesday, 15 April 2009
Metal-organic frameworks (MOFs) are nanoporous materials with structures
tailorable to favor the adsorption of specific analytes. Their non-rigid nature
leads to changes in their structure which, if coupled to a microcantilever, can
be detected via the stress induced at an interface. We integrated a MOF thin
film with a microcantilever and show that surface stresses can be converted to
mechanical energy to create a responsive, reversible, and selective sensor. We
discuss MOF properties, integration with MEMS sensors, gas testing, and
computational modeling. MOFs hold great promise for creating recognition
chemistries to enable selective detection of a wide range of analytes.
Stand-off detection of organic samples using filament-induced breakdown
spectroscopy (Paper Presentation)
Paper 7306A-37 of Conference 7306A
Authors(s): James Martin, Matthieu Baudelet, Matthew Weidman, Matthew K. Fisher,
Candice Bridge, Christopher G. Brown, Michael Sigman, Martin C. Richardson,
College of Optics & Photonics, Univ. of Central Florida (United States); Paul J.
Dagdigian, The Johns Hopkins Univ. (United States)
Date: Wednesday, 15 April 2009
As an alternative to focused nanosecond pulses for stand-off LIBS detection of
energetic materials, we use self-channeled femtosecond pulses (35 fs, 25 mJ)
from a Ti:Sapphire laser to produce filaments up to 50 meters and create a
plasma on energetic material samples.
Light collection challenge is done via an off–axis Newtonian telescope (30 cm of
diameter and 190 cm focal length). Signal characterizations are made for several
distances of detection.
Finally, sample detection and discrimination from background signal, are
achieved through chemometrics signal processing to improve the organic material
detection.
New high-gain detectors for active imaging (Paper Presentation)
Paper 7298-106 of Conference 7298
Authors(s): Frederic P. Pistone, Philippe M. Tribolet, Michel M. Zecri, Xavier
Lefoul, SOFRADIR (France); Gérard L. Destéfanis, Yohan Rothman, Commissariat à
l'Energie Atomique (France)
Date: Thursday, 16 April 2009
New applications require high sensitivity infrared (IR) sensors in order to
detect very low incident fluxes. Laser gated imaging has, in particular,
additional specific needs. IR sensors for this type of application are
synchronized with eye-safe lasers, and have to detect a weak signal
backscattered from the target on the order of 10 photons per pulse. They also
have to be able to operate with a very short integration time, typically one
hundred nanoseconds, in order to gate the backscattered signal around the
target. In partnership with Sofradir, CEA/LETI (France) has developed high
quality HgCdTe avalanche photodiodes satisfying these requirements. In parallel,
specific studies have been carried out at the Read-Out Circuit level to develop
optimized architectures. Thanks to these advances, a new Integrated Dewar
Detector Cooler Assembly has been developed. This new product is the first step
in a road-map to address low flux infrared sensors in the next few years.
Experimental characterization of mm-wave detection by a micro-array of Golay
cells (Paper Presentation)
Paper 7309-18 of Conference 7309
Authors(s): Douglas Denison, Michael E. Knotts, Georgia Tech Research Institute
(United States); Vladimir Tsukruk, Michael E. McConney, Georgia Institute of
Technology (United States)
Date: Thursday, 16 April 2009
We present experimental results for an uncooled imaging focal plane array
technology that consists of a novel polymer/nanoparticle monolayer/polymer
layered membrane suspended over a micro-fabricated array of cavities. This Golay-like
device demonstrates an NEP of 300 nW/sqrt(Hz) at 105 GHz for a 19-layer membrane
suspended over an array of 80 micron diameter cavities. Calculations of membrane
sensitivity show that this NEP could be reduced to ~ 100 pW/sqrt(Hz) with
enlarged cavity diameters on the order of 600 microns.
Electrospun sol-gel fibers for FRET-based sensing (Paper Presentation)
Paper 7313-17 of Conference 7313
Authors(s): Jasenka Memisevic, Lela Riley, Sheila A. Grant, Univ. of Missouri,
Columbia (United States)
Date: Friday, 17 April 2009
A fluorescent platform mesh was constructed by utilizing electrospinning
techniques. Incorporating cetyltrimethylammonium bromide, as well as
fluorescence dyes in the sol-gel, resulted in the formation of a dye-doped
fibrous mesh. After formation of the fibers, pore-creating techniques were
applied, resulting in a high surface area material. Fluorescently labeled
antibodies were immobilized onto the nanoporous fibrous mesh, which created a
highly responsive FRET immunosensor, with the fluorescent fiber platform
donating energy to the acceptor on the antibody. Addition of the Helicobacter
pathogen causes measurable FRET. Results show that the sensor exhibits high
sensitivity and reliability due to the increased surface area.
A multimodal technique for the quantification of dynamic stress (Poster
Presentation)
Paper 7313-26 of Conference 7313
Authors(s): Vishal Saxena, Univ. of Southern California (United States) and
AppWave (United States)
Date: Thursday, 16 April 2009
We report a multimodal optical technique based on near infrared spectroscopy and
mid infrared imaging as a non-invasive, in-vivo tool for monitoring the vascular
status of flexor pollicis brevis (thenar muscle of hand), and the physiological
changes that occur during physical exercise. A technique based on the
combination of near infrared spectroscopy technique namely; steady state diffuse
optical spectroscopy (SSDOS: 650-850 nanometers) is applied for monitoring
changes in tissue blood oxygen saturation, while simultaneous mid infrared
imaging (MIRI: 8-12 micrometers) provides information about the thermodynamics
of heat dissipation during prolonged physical exercise. The proposed technique
is likely to provide insight into muscle physiology, therapeutic response and
treatment.
A quantitative measure for information content in antenna array radiation
patterns (Paper Presentation)
Paper 7310-11 of Conference 7310
Authors(s): Karan D. Mohan, Mohammad A. Khan, Amin N. Dharamsi, Old Dominion
Univ. (United States)
Date: Tuesday, 14 April 2009
We present a novel approach to quantifying and optimizing the amount of
information available in radiation patterns of antenna arrays. The technique is
applicable on a broad scale, with applications in infrared, nanophotonics and
other non-intrusive sensing techniques. We investigate the amount of information
lost due to distortions and noise in the environment, and due to other
limitations of the detector system, based on Shannon’s information principles.
While we focus on the information content, in bits, of antenna array radiation
patterns, the method presented is general and may be applied to a variety of
distributions.
Mid-IR transparent materials based on rare-earth aluminate glass ceramics (Paper
Presentation)
Paper 7302-41 of Conference 7302
Authors(s): Anatoly Rosenflanz, Jean Tangeman, Amy Barnes, Steven Lenius, 3M Co.
(United States)
Date: Thursday, 16 April 2009
Rapid quenching followed by viscous sintering within a range of stability of a
supercooled liquid (i.e. between Tg and Tx) has been utilized to prepare bulk
aluminate glasses modified by rare-earths and, optionally, zirconia. When
kinetically relaxed during re-heating, such glasses hypernucleate, forming
nanostructured glass-ceramics. In this presentation we report utilization of
this technique for preparation of mid-IR transparent materials with durabilities
similar to spinel, ALON and sapphire. The existence of an intermediate “soft”
glassy stage is however perceived as an advantage over these materials due to
shaping and finishing ability via molding or direct machining. Recent advances
in transparencies will also be described.
Fully printed phased-array antenna for space communications (Poster
Presentation)
Paper 7318-58 of Conference 7318
Authors(s): Maggie Y. Chen, Omega Optics, Inc. (United States); Xuejun Lu, Univ.
of Massachusetts, Lowell (United States); Harish Subbaraman, Ray T. Chen, The
Univ. of Texas at Austin (United States)
Date: Thursday, 16 April 2009
In this paper, we report a fully printed 5.6GHz flexible phased array antenna.
The PAA is printed out at room temperature on 100μm thick Kapton substrate. The
FET switch in the phase shifter for the 2-bit 2-element phased-array antenna is
based on carbon nanotube network in solution, which has carrier mobility as high
as 46770cm2/V•s. The FET switch exhibits a switching speed of 0.2ns and works
well for 5.6GHz RF signal. The small signal modulation and spectrum linearity is
measured at 5GHz, versus the state-of-art flexible FET operating frequency of
52MHz. The switching voltage we used is 2V, while the state-of-art flexible FET
has a gate voltage around 50V.
Using of SAMs technology for label-free detection of pathogenic micro-organisms
(Paper Presentation)
Paper 7318-15 of Conference 7318
Authors(s): Erhan Piskin, Hacettepe Üniv. (Turkey)
Date: Wednesday, 15 April 2009
Bioanalytical systems based on optical detection of biosensing elements could
find wide applications in DNA analysis, drug discovery, medical diagnostics,
environmental monitoring as well as in protection against bioterrorism. Here, we
will demonstrate that our experience related to preparation of SAMs having
various ending groups (i.e., amino, thiol, methyl, hydroxyl) on the different
solid substrates and also different lithography techniques based on
photolithography and template synthesis method using nano-structured anodic
alumina films for the patterning of surfaces to detect microorganisms (i.e.,
Mycobacterium tuberculosis and Avian influenza) were investigated by surface
Plasmon Resonance (SPR) and Ellipsometric biosensors.
Mass fabrication tolerances for integrated optical sensors (Paper Presentation)
Paper 7322-6 of Conference 7322
Authors(s): Jeroen A. W. Van Houwelingen, Mirvais Yousefi, Michael Engelmann,
Ruud Schmits, Hans van den Berg, TNO (Netherlands)
Date: Thursday, 16 April 2009
Research in Integrated Nano Photonics (INP) has made great progress in recent
years. One of the driving forces behind the research is the large potential that
INP based devices have as ultra compact and highly sensitive sensors. We will
present the manufacturing possibilities and challenges of using CMOS standards
to fabricate Silicon on insulator (SOI) INP devices. In particular an analysis
of edge tolerance and influence is presented as well as the manufacturing of a
basic ring-resonator structure that is suitable for sensing.
Low-thermal expansion infrared glass ceramics (Paper Presentation)
Paper 7302-40 of Conference 7302
Authors(s): Philip Lam, L2 Tech, Inc. (United States)
Date: Thursday, 16 April 2009
An innovative 3-5 micron infrared-transparent glass ceramic material is
developed to have ultra-low thermal expansion over a wide temperature range and
high thermal-shock resistance to be used as windows and domes for high speed
flight. The material is an inorganic, non-porous glass ceramic, characterized by
crystalline phases of evenly distributed nano-crystals of negative thermal
expansion within a residual glass phase.
Synthesis and properties of eye-safe sesquioxide single crystal and transparent
ceramic laser sources (Paper Presentation)
Paper 7325-3 of Conference 7325
Authors(s): Colin D. McMillen, John M. Ballato, Joseph W. Kolis, Baris Kokuoz,
Basak Y. Kokuoz, Karn Serivalsatit, Exley McCormick, Clemson Univ. (United
States)
Date: Monday, 13 April 2009
Recently we have developed novel approaches to the preparation of single
crystals and transparent ceramics based on scandia, yttria and lutetia for use
as high average power eye-safe laser sources. We have demonstrated the
hydrothermal single crystal growth of optically clear single crystals of Sc2O3,
Lu2O3 and Er:Sc2O3 having dimensions up to 1 cm. Additionally, we will present
novel processing and sintering routes that we have used to prepare yttria and
Er:Y2O3 transparent ceramics having nanoscale grain sizes. When possible, direct
comparisons of the properties of these single crystal and transparent ceramic
hosts will be presented.
Toward in-situ detection of PAHs trace in seawater using SERS-active sensors
(Paper Presentation)
Paper 7312-12 of Conference 7312
Authors(s): Olivier Péron, Emmanuel Rinnert, Michel Lehaitre, Florent Colas,
Chantal Compère, French Research Institute for Exploitation of the Sea (France)
Date: Monday, 13 April 2009
The development of in-situ sensors suitable for environmental analysis in
sea-water is proposed. Surface-enhanced Raman scattering (SERS) active
substrates based on gold nanostructures were synthesized to detect polycyclic
aromatic hydrocarbons (PAHs). In such an approach, PAHs were preferentially
immobilized on the hydrophobic sensor surface and naphthalene or pyrene were
detected at 10ppb in artificial sea-water with a low incident laser power
(~0.1mW) and a short integration time (10s). SERS substrates can be integrated
to our home-made in-situ Raman spectrometer coupled to a microfluidic system.
Such a device is now ready to use to confirm PAHs detection during offshore
experiments.
Mid-IR intracavity OPO (Paper Presentation)
Paper 7325-16 of Conference 7325
Authors(s): Santosh N. Pisharody, Yusong Yin, Photonics Industries
International, Inc. (United States)
Date: Monday, 13 April 2009
LIDAR measurements of biological warfare simulants (Paper Presentation)
Paper 7304-9 of Conference 7304
Authors(s): David M. Brown, Evan P. Thrush, Karen M. Siegrist, Michael E.
Thomas, Alison Carr, Nathan T. Boggs, The Johns Hopkins Univ. Applied Physics
Lab. (United States)
Date: Tuesday, 14 April 2009
A chamber aerosol LIDAR is being developed to perform well-controlled tests of
optical scattering characteristics of biological aerosols, including Bacillus
atrophaeus (BG) and Bacillus thuringiensis (BT), for validation of optical
scattering models. The 1.064 µm, sub-nanosecond pulse LIDAR allows for sub-meter
resolution of particle depolarization ratio at 1 kHz repetition rate. Automated
data acquisition and analysis provide real-time analysis or recording. Tests
administered within the refereed 1 cubic meter chamber can provide high quality
near-field backscatter measurements devoid of interference from entrance and
exit window reflections. Initial chamber measurements of BT depolarization ratio
at a variety of concentrations are presented.
Porphyrin-embedded organosilicas for detection and decontamination (Paper
Presentation)
Paper 7306A-14 of Conference 7306A
Authors(s): Brandy J. Johnson, Brian J. Melde, Paul T. Charles, Anthony P.
Malanoski, Michael A. Dinderman, Naval Research Lab. (United States)
Date: Tuesday, 14 April 2009
Porphyrin-embedded materials (PEMs) combine tunable binding selectivity, high
surface area, and low materials density of a highly ordered pore network with
the unique properties of porphyrins. Porphyrins are a family of large, nearly
planar molecules which strongly absorb visible light and fluoresce intensely.
They are highly sensitively to alterations in their immediate environment making
porphyrins valuable as indicators for small molecule contaminants. They can be
synthesized with high surface areas, uniform pore dimensions, and ordered
nanostructures while incorporating organic bridging groups in the pore walls
that may be tuned for adsorption of a specific class of compounds. The materials
can be stored under ambient conditions and offer exceptional shelf-life.
Third-order nonlinear optical properties and its limiting behavior of
polyaniline/SiO2 composite materials (Poster Presentation)
Paper 7325-32 of Conference 7325
Authors(s): Yun-Dong Zhang, Lei Ma, Ping Yuan, Harbin Institute of Technology
(China)
Date: Tuesday, 14 April 2009
Polyaniline are promising molecules which present very attractive properties for
nonlinear optical applications. The third-order nonlinear optical properties of
polyaniline/SiO2 (PANI/SiO2) composite materials were studied using the single
beam Z-scan technique. These molecules exhibit a strong reverse saturable
absorption with a doubled frequency Nd:YAG laser pulses with nanosecond at 532
nm. The nonlinear absorption coefficient (β) and nonlinear refractive index (n2)
was retrieved by fitting experimental data. And their optical limiting
performance has been investigated. The result show the polyaniline/SiO2 (PANI/SiO2)
composite materials have good nonlinear optical properties and optical limiting
performance.
Smart dust infrared sensors for standoff explosives detection (Paper
Presentation)
Paper 7304-47 of Conference 7304
Authors(s): Alexey E. Kovalev, Matthew G. Bray, Theresa S. Mayer, Douglas H.
Werner, The Pennsylvania State Univ. (United States)
Date: Thursday, 16 April 2009
We demonstrate a prototype sensor based on a new eye-safe detection strategy
with the potential to report the presence trace explosives from standoff
distances of up to 100 m. The method detects the reflected infrared radiation
from groups of micron-sized chemically-sensitized metallodielectric
nanostructures. Specifically, the sensors change from reflecting to absorbing
nearly 100% of the incident probe beam radiation over a narrow band of mid-IR
wavelengths when explosive vapor is present. This strategy is not limited to the
detection to explosives, but can also be used to detect other threats by
modifying the chemically-sensitive layers of the nanostructure.
Supercontinuum lidar measurements of atmospheric constituents (Paper
Presentation)
Paper 7323-32 of Conference 7323
Authors(s): Perry S. Edwards, David M. Brown, Andrea M. Wyant, Zhiwen Liu, C.
Russell Philbrick, The Pennsylvania State Univ. (United States)
Date: Thursday, 16 April 2009
Extending our developments of a previously reported supercontinuum lidar system
has increased the capability for measuring long path atmospheric concentrations.
The multi-wavelength capability of the supercontinuum laser source has the
advantage of obtaining multiple line differential absorption spectra
measurements to determine the concentrations of various atmospheric
constituents. Simulation software such as MODTRAN TM 5 has provided the means to
compare and evaluate the experimental measurements. Improvements to the
nanosecond supercontinuum laser fiber coupled transceiver system have allowed
open atmospheric path lengths greater than 600 m. Analyses of species
concentrations attained from horizontal paths over a heavy use urban area are
presented.
Atmosphere issues in detection of explosives and organic residues (Paper
Presentation)
Paper 7304-50 of Conference 7304
Authors(s): Christopher G. Brown, Matthieu Baudelet, Candice Bridge, Matthew K.
Fisher, Michael Sigman, Martin C. Richardson, College of Optics & Photonics,
Univ. of Central Florida (United States); Paul J. Dagdigian, The Johns Hopkins
Univ. (United States)
Date: Thursday, 16 April 2009
Studies have shown that ionized atmospheric nitrogen and oxygen during the
plasma formation interfere in a LIBS analysis under atmosphere . This becomes
important when detecting explosives, because of their higher concentrations of
nitrogen and oxygen compared to the carbon and hydrogen in non-energetic
materials.
This study makes a comparison of LIBS analysis on organic thin residues on a
non-metallic substrate by nanosecond and femtosecond lasers in air and argon
atmospheres. Principle Component Analysis (PCA) was used to identify the
influence of atmosphere for sample discrimination via the emission spectra and
validated using Receiver Operating Characteristics (ROC) curves.
Gigahertz bandwidth photon counting (Paper Presentation)
Paper 7320-5 of Conference 7320
Authors(s): William H. Farr, Jonathan W. Gin, Danh H. Nguyen, Jet Propulsion
Lab. (United States)
Date: Tuesday, 14 April 2009
Early applications driving the development of single photon detectors simply
required low noise performance with kiloHertz and lower count rate requirements
and minimal or no timing resolution. Newer applications can require photon
counting at flux rates into megaphoton or gigaphoton per second regimes coupled
with sub-nanosecond timing accuracy. We have developed and implemented systems
for deep space optical communications to both characterize gigaHertz bandwidth
single photon detectors as well as process photon count signals at rates beyond
100 megaphotons per second to implement communications links at data rates
exceeding 100 megabits per second with efficiencies greater than two bits per
detected photon. We shall review our methods and characterization results for
detectors such as intensified photodiodes, superconducting nanowire detectors,
and negative avalanche feedback photon counters.
Super-bright, stable, reproducible, SERS biotags for simultaneous identification
of multiple biomarkers (Paper Presentation)
Paper 7321-1 of Conference 7321
Authors(s): Martin Moskovits, Norbert Reich, Gary Braun, SeungJoon Lee, Univ. of
California, Santa Barbara (United States)
Date: Monday, 13 April 2009
Biotags based on polymer coated, silver nanoparticle aggregates tethered with
bifunctional ligands were developed that produce surface-enhanced Raman spectra
(SERS) with intensities exceeding most intense fluorophores. The narrow SERS
band widths allows the spectra of a dozen or more SERS bio-tags to be
deconvoluted out of a single spectrum. The precise nano-engineering of these
tags and the careful control of their synthesis produce nanosystems with highly
reproducible properties and great stability – solving a long-standing problem
with SERS substrates. Their use in extra- and intra-cellular applications and as
in vivo imaging agents will be illustrated.
Mechanisms of frictional adhesion in biological adhesion and locomotion (Paper
Presentation)
Paper 7321-12 of Conference 7321
Authors(s): Jacob Israelachvili, Kimberly L. Turner, Hongbo Zeng, Univ. of
California, Santa Barbara (United States); Noshir Pesika, Tulane Univ. (United
States); Boxin Zhao, Univ. of Waterloo (Canada); Sathya S. Chary, John Tamelier,
Univ. of California, Santa Barbara (United States)
Date: Monday, 13 April 2009
Using the Surface Forces Apparatus (SFA) and other techniques we have carried
out various experiments at the nano- to macro-scales to measure the forces
between biological surfaces and non-biological substrates to establish how
certain animals, from geckos to mussels, adhere to surfaces under a wide range
of conditions (both in air and seawater), and especially how rapid adhesion
(sticking) can be followed by rapid detachment to allow for rapid movement
(running) on walls and ceilings.
We describe the very different processes occurring on attachment and detachment,
which appear to involve the whole hierarchy of length scales of animals. We
consider whether there is some general model for the biomechanics and
biodynamics of apparently quite different biological systems, and describe our
attempts to develop a process that mimics biological systems.
MEMS-based warm gas thruster system for CubeSat orbital maneuver applications
(Paper Presentation)
Paper 7331-15 of Conference 7331
Authors(s): Po-Hao A. Huang, Univ. of Arkansas (United States); Eui-Hyeok Yang,
Stevens Institute of Technology (United States)
Date: Monday, 13 April 2009
This paper reports the ongoing development effort combining the previously
developed attitude control thruster system with a high pressure piezoelectric
microvalve. The goal is to provide orbital maneuver capabilities for future Air
Force and NASA nano/pico-satellite missions, such as inspector satellites for
post launch diagnostics, sparse array antennas, field measurements of space
weather events, and the calibration of atmospheric drag in the thermosphere. The
piezoelectric microvalve used is low power (3mW), high speed (30µs), and high
pressure (70 bar absolute). The target warm gas Newton level propulsion system
dry mass is 200 grams and with a volume of <100 cm3.
Fast detection and identification of bacteria in potable water (Paper
Presentation)
Paper 7304-5 of Conference 7304
Authors(s): Alois Friedberger, Ulrich Reidt, Christoph Heller, Andreas Helwig,
Gerhard Müller, EADS Deutschland GmbH (Germany)
Date: Tuesday, 14 April 2009
The quality and safety of drinking water is of major importance for human life.
Current analytical methods for viable bacteria in potable water are time
consuming due to a required cultivation step. Fast detection of pathogenic
microorganisms with high sensitivity and selectivity is still a challenge. Under
normal circumstances, the concentration of pathogens is extremely low; thus an
enrichment step is necessary before analysis of the water sample. We use
micromechanical filters with nano-sized pores to capture and enrich bacteria and
fungi on the filter surface and making them accessible to different detection
methods.
Biomolecular detection using optofluidics (Paper Presentation)
Paper 7322-1 of Conference 7322
Authors(s): David Erickson, Cornell Univ. (United States)
Date: Thursday, 16 April 2009
In this talk I will discuss two new technologies we are developing that fuse
traditional microfluidic elements with sub-wavelength scale nanophotonic
structures to create sensitive, specific, and highly parallel “optofluidic”
biomolecular sensors. The first approach I will discuss will involves the use of
high-quality factor, low mode volume optical resonators which rely on detecting
minute changes in refractive index following a molecular binding event.
Following this I will also discuss our preliminary efforts to develop devices
for on-chip surface enhanced Raman spectroscopy (SERS) based biomolecular
detection. In both cases preliminary data will be presented demonstrating
serotype specific detection of Dengue virus. Throughout the talk I will discuss
the advantages and disadvantages of these approaches in the context of
traditional label free technologies (such as surface plasmon resonance) and
other emerging nano-technological approaches.
New microcavity substrates for enhancing Raman signals of microscopic samples
(Paper Presentation)
Paper 7313-14 of Conference 7313
Authors(s): Shiv K. Sharma, Anupam K. Misra, Lori Kamemoto, Ava Dykes, Tayro
Acosta, Univ. of Hawai'i (United States)
Date: Thursday, 16 April 2009
A novel method for improving the detection limit of normal Raman spectra of
chemicals in pico-liters volume will be presented. A micro-cavity substrate uses
various mechanisms that collectively improve the normal Raman signal from the
sample without SERS. The micro-cavity substrate enhances the entire Raman
spectra of the molecules under investigation and maintains the relative
intensity ratios of the various Raman bands. It will be further shown that
micro-cavities coated with nano films of gold and silver takes advantage of both
SERS and micro-cavity method and significantly improve the detection limits of
samples.
Show Abstract
In this talk I will discuss two new technologies we are developing that fuse
traditional microfluidic elements with sub-wavelength scale nanophotonic
structures to create sensitive, specific, and highly parallel “optofluidic”
biomolecular sensors. The first approach I will discuss will involves the use of
high-quality factor, low mode volume optical resonators which rely on detecting
minute changes in refractive index following a molecular binding event.
Following this I will also discuss our preliminary efforts to develop devices
for on-chip surface enhanced Raman spectroscopy (SERS) based biomolecular
detection. In both cases preliminary data will be presented demonstrating
serotype specific detection of Dengue virus. Throughout the talk I will discuss
the advantages and disadvantages of these approaches in the context of
traditional label free technologies (such as surface plasmon resonance) and
other emerging nano-technological approaches.
Protein nanoarray made by size-dependent self-assembly for detection of mouse
immunoglobulin G and octamer-4
Paper 7313-5 of Conference 7313
Date: Thursday, 16 April 2009
Author(s): Phat L. Tran, Tremaine B. Powell, Keesung Kim, Jeong-Yeol Yoon, The
Univ. of Arizona (United States)
Show Abstract
A protein nanoarray is created when submicro and nano beads, varying in their
size and each conjugated with different proteins, self-assemble to specific
locations depending on the diameter matching the surface electron beam patterns
created. Protein binding is confirmed from the fluorescence attenuation and FRET
upon antigen-antibody binding on the bead surface. We tested this system for
mouse immunoglobulin G (positive control) and Octamer-4 (a transcription factor
from embryonic stem cells). This method, called size-dependent self-assembly,
allows control of the location of each type of bead, and thus, control of the
location of multiple proteins.
New microcavity substrates for enhancing Raman signals of microscopic samples
Paper 7313-14 of Conference 7313
Date: Thursday, 16 April 2009
Author(s): Shiv K. Sharma, Anupam K. Misra, Lori Kamemoto, Ava Dykes, Tayro
Acosta, Univ. of Hawai'i (United States)
Show Abstract
A novel method for improving the detection limit of normal Raman spectra of
chemicals in pico-liters volume will be presented. A micro-cavity substrate uses
various mechanisms that collectively improve the normal Raman signal from the
sample without SERS. The micro-cavity substrate enhances the entire Raman
spectra of the molecules under investigation and maintains the relative
intensity ratios of the various Raman bands. It will be further shown that
micro-cavities coated with nano films of gold and silver takes advantage of both
SERS and micro-cavity method and significantly improve the detection limits of
samples.
Nanocrystalline Cu-doped zirconia film-coated long-period fiber grating for CO
monitoring at high temperature
Paper 7322-11 of Conference 7322
Date: Thursday, 16 April 2009
Author(s): Xiling Tang, Jian Zhang, Junhang Dong, Univ. of Cincinnati (United
States); Tao Wei, Hai Xiao, Missouri Univ. of Science and Technology (United
States)
Show Abstract
Physically and functionally integrating materials with special properties into
miniaturized single device is one of the central themes of intelligent
technology development. The integrated devices can either offer enhanced
functionality or realize the unique capabilities of the constituting materials
that otherwise cannot be accessed by the individual material alone. Recently, we
have successfully integrated various nano-structured inorganic thin films with
long-period fiber grating (LPFG) as fiber optic sensors for gas measurement in
different conditions. Here we report the development of Cu-doped zirconia (CDZ)
nanocrystalline thin-film coated LPFG sensors for in-situ high temperature CO
monitoring.
Nanomaterials and nanostructures research for integrated adaptive multimodal
sensing (Keynote Presentation)
Paper 7318-33 of Conference 7318
Date: Friday, 17 April 2009
Author(s): Kitt C. Reinhardt, Air Force Office of Scientific Research (United
States)
Show Abstract
An overview of AFOSR sponsored research in novel integrated multi-mode
(intensity, wavelength, polarization, phase, etc.) sensor concepts will be
presented. Research approach and progress achieved toward various innovative
concepts for near-real time tuning of sense-mode ‘select’ and pixel location
‘read’ functions will be presented; including very recent developments in
transparent electronics/interconnects and lattice-mismatched absorber materials
enabling for vertically-integrated multi-modal pixel concepts. Of special
interest is recent progress in absorption band-edge engineering and dynamic
tuning resulting from synthesis of innovative homogeneous and heterogeneous
structures based on combinations of one or more 0D, 1D, and 2D quantum and nano-based
assemblies and interactions.
EO/IR sensors development using zinc oxide and carbon nanostructures
Paper 7318-3 of Conference 7318
Date: Wednesday, 15 April 2009
Author(s): Ashok K. Sood, Robert A. Richwine, Yash R. Puri, Magnolia Optical
Technologies, Inc. (United States); Dennis L. Polla, Nibir K. Dhar, Defense
Advanced Research Projects Agency (United States); Zhonglin L. Wang, Georgia
Institute of Technology (United States); Priyalal S. Wijewarnasuriya, Army
Research Lab. (United States); Neil Goldsman, Univ. of Maryland, College Park
(United States); Martin B. Soprano, U.S. Army (United States)