The UCLA Biophysics Neuroimaging Laboratory is committed to developing new
microscopy techniques to further the reach of experimental methods in the area
of systems neuroscience.
The Lab is collaborating to develop next generation multi-photon microscopy
systems, with the aim of imaging millimeter volumes of tissue with non-linear
enhanced resolution at millisecond time scales. This may improve methods for
analysis of in-vivo cortical circuits and classic microcircuit systems via
calcium and potentiometric dyes, provide higher throughput for structural
imaging, and enable more detailed modeling of systems of nerve cells. Calcium
and potentiometric dyes can be used to monitor network activity with single cell
and single spike resolution across hundreds of cells.
Featured in the laboratory is an ultrafast Ti:Sa oscillator kit from Del Mar
Photonics. Output power is typically hundreds of milliwatts. KLM Mode locking is
started by voice coil and monitor high bandwidth avalanche photodiode combined
with a lock-in amplifier.
In this video Adrian Cheng shows his multiphoton imaging system based on Del Mar
Photonics Ti:Sapphire laser and describes his experiments on imaging of neural
activity in zebra fish.
Del Mar Photonics Ti:Sapphire lasers in combination with a new bread of DPSS and fiber pump lasers bring down the cost of femtosecond laser systems for non-linear imaging and allows more researches to have this powerful research tool in their labs.
| Laser brand-name | Brief description | Output parameters | Sample specifications | Pdf brochures |
| Trestles | Ti:Sapphire oscillator | wavelength tuning range 710-950 nm (@6W pump); output power >600 mW (@6W pump, 800 nm) pulse duration <20 fs - 100 fs |
Trestles-100 without pump laser Ti:Sapphire oscillator having a tuning range of 710-950 nm (@6W pump); output power >600 mW (@6W pump, 800 nm); beam quality TEMoo; polarization - linear horizontal; pulse duration <100 fs; repetition rate 80 MHz |
Trestles
Ti:Sapphire laser Trestles Finesse Ti:Sapphire laser Manual Pump lasers DPSS DMPLH lasers HPG DPSS green laser Finesse DPSS green laser Green fiber laser - NEW! |
The UCLA Biophysics
Neuroimaging Laboratory
The UCLA Biophysics Neuroimaging Laboratory is located in Knudsen Hall Room
B-171 next to the Physics and Astronomy Building (PAB)
Request a quote for Trestles Ti:Sapphire laser
When requesting a quote please indicate required output power and tuning range. Otherwise, you can indicate available budget and we'll quote you a system that will fit in specified amount.
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