New Laser Focus Webcast scheduled for Thursday, April 26th, 2007 1:00PM EDT |
17:00 GMT
Ultrafast 2-D Vibrational Echo Experiments
with Applications in Chemistry and Biology
Ultrafast 2D-IR vibrational echo experiments are akin to 2D NMR but operate on
time scales 6 to 10 orders of magnitude faster than NMR. The method is
illustrated with chemical exchange experiments that directly observe
solute-solvent complex formation and dissociation, as well as isomerization
around a carbon-carbon single bond. Experiments on proteins and enzymes measure
structural dynamics and the influence of substrate binding on enzyme dynamics.
Speaker:
Michael D. Fayer, Professor of Chemistry, Stanford University
http://www.laserfocusworld.com/resourcecenter/webcasts/webcastDetails.html?id=379
To register: http://www.iian.ibeam.com/events/penn001/22149
All members of Del Mar Photonics R&D team are encouraged to register!
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Are you a graduate or undergraduate student currently working in Ultrafast
2-D Vibrational Echo experiments?
We have part time job opportunity for you with potential full time employment in
the future! Please
send us description of your experience in Ultrafast Dynamics research!
Del Mar Photonics team includes industry veterans, bright young researches
and engineers as well as strong team of part time and seasonal sales personnel
and ready to join our team students and graduated students, currently working
with us on a part time basis.
Related Publications
“Ultrafast
Solute-Solvent Complex Chemical Exchange Observed in Real Time: Multidimensional
Vibrational Echo Correlation Spectroscopy,” Junrong Zheng, Kyungwon Kwak, John
Asbury, Xin Chen,
“Dynamics
of Water Probed with Vibrational Echo Correlation Spectroscopy,” John B. Asbury,
Tobias Steinel, Kyungwon Kwak, S. A. Corcelli, C. P. Lawrence, J. L. Skinner,
and M. D. Fayer, J. Chem. Phys. 121, 12431-12446 (2004).
“Vibrational Echo Correlation
Spectroscopy Probes of Hydrogen Bond
Dynamics in Water and Methanol,” John B. Asbury, Tobias Steinel, and M. D. Fayer,
J. Lumin. 107, 271-286 (2004).
“Using Ultrafast Infrared Multidimensional
Correlation Spectroscopy to Aid in Vibrational Spectral Peak Assignments,” John
B. Asbury, Tobias Steinel, M. D. Fayer, Chem. Phys. Lett. 381, 139-146
(2003).
2006
Water Penetration into Protein Secondary Structure Revealed by
Hydrogen-Deuterium Exchange Two-Dimensional Infrared Spectroscopy L.P. DeFlores
and A. Tokmakoff, J. Am. Chem. Soc., (2006).
Multidimensional infrared spectroscopy of water. I. Vibrational dynamics in
two-dimensional IR line shapes J. J Loparo, S. T. Roberts, and A. Tokmakoff, J.
Chem. Phys. 125, 194521, (2006).
Multidimensional infrared spectroscopy of water. II. Hydrogen bond switching
dynamics J. J Loparo, S. T. Roberts, and A. Tokmakoff, J. Chem. Phys. 125,
194522, (2006).
Characterization of spectral diffusion from two-dimensional line shapes S. T.
Roberts, J. J Loparo, and A. Tokmakoff, J.Chem. Phys, 125, 084502 (2006).
Spectral Signatures of Heterogeneous Protein Ensembles Revealed by MD
Simulations of 2DIR Spectra Z. Ganim and A. Tokmakoff, Biophysical Journal, 91,
2636-2646 (2006).
The Anharmonic Vibrational Potential and Relaxation Pathways of the Amide I and
II Modes of N-Methylacetamide L. P. DeFlores, Z. Ganim, S. F. Ackley, H. S.
Chung, and A. Tokmakoff, J. Phys. Chem. B, 110(38), 18973-18980 (2006).
Single-shot two-dimensional spectrometer M. F. DeCamp, and A. Tokmakoff, Opt.
Lett., 31, 113-115 (2006).
Visualization and Characterization of the Infrared Active Amide I Vibrations of
Proteins H. S. Chung, and A. Tokmakoff, J. Phys. Chem. B, 110, 2888-2898 (2006).
2005
Hydrogen bonds in liquid water are broken only fleetingly J. D. Eaves*, J. J.
Loparo*, C. J. Fecko, S. T. Roberts, A. Tokmakoff, and P. L. Geissler, PNAS,
102, 13019-13022 (2005).
Electric Field Fluctuations Drive Vibrational Dephasing in Water J. D. Eaves, A.
Tokmakoff, and P. L. Geissler, J. Phys. Chem. A, 109(42), 9424-9436 (2005).
Residual Native Structure in a Thermally Denatured b-Hairpin A. W. Smith, H. S.
Chung, Z. Ganim, and A. Tokmakoff, J. of Phys. Chem. B, 109, 17025-17027 (2005).
Upconversion multichannel infrared spectrometer M. F. DeCamp, and A. Tokmakoff,
Opt. Lett., 30, 1818-1820 (2005).
Amide I Vibrational Dynamics of N-Methylacetamide in Polar Solvents: The Role of
Electrostatic Interactions M. F. DeCamp, L. P. DeFlores, J. M. McCracken, A.
Tokmakoff, K. Kwac, and M. Cho, J. of Phys. Chem. B, 109, 11016-11026 (2005).
Conformational changes during the nanosecond-to-millisecond unfolding of
ubiquitin. H. Chung, M. Khalil, A. W. Smith, Z. Ganim, and A. Tokmakoff, PNAS,
102, 612-617 (2005).
Local hydrogen bonding dynamics and collective reorganization in water:
Ultrafast infrared spectroscopy of HOD/D2O. C.J. Fecko, J. J. Loparo, S. T.
Roberts, and A. Tokmakoff, J. Chem. Phys, 122, 054506 (2005).
2004
Reorientational and configurational fluctuations in water observed on the
molecule length scales. J. J. Loparo, C.J. Fecko, J.D. Eaves, S. T. Roberts, and
A. Tokmakoff, Phys. Rev. B, 70, 180201 (2004).
Nonlinear infrared spectroscopy of protein conformational change during thermal
unfolding. H. Chung, M. Khalil and A. Tokmakoff, J. Phys. Chem. B, 108, 15332
(2004).
Two-dimensional infrared spectroscopy of antiparallel b-sheet secondary
structure. N. Demirdöven, C. M. Cheatum, H. Chung, M. Khalil, J. Knoester and A.
Tokmakoff, J. Am. Chem. Soc., 126, 7981(2004).
Vibrational coherence transfer characterized with Fourier-transform 2D IR
spectroscopy. M. Khalil, N. Demirdöven and A. Tokmakoff, J. Chem. Phys, 121, 362
(2004).
Generation of 45 femtosecond pulses at 3 mm with a KNbO3 optical parametric
amplifier. C. J. Fecko, J. J. Loparo and A. Tokmakoff, Optics Communications,
241, 521-528 (2004).
2003
Signatures of b-sheet secondary structures in linear and two-dimensional
infrared spectroscopy. C. M. Cheatum, A. Tokmakoff, and J. Knoester, J. Chem.
Phys., 120, 8201 (2003).
Coherent 2D IR Spectroscopy: Molecular Structure and Dynamics in Solution. M.
Khalil, N. Demirdoven, A. Tokmakoff, J. Phys. Chem. A., 107, 5258-5279(2003).
Polarization-selective femtosecond Raman spectroscopy of low-frequency motions
in hydrated protein films. J. D. Eaves, C. J. Fecko, A. L. Stevens, P.l Peng and
A. Tokmakoff, Chem. Phys. Let., 376 (2003)
Ultrafast Hydrogen-Bond Dynamics in the Infrared Spectroscopy of Water. C. J.
Fecko, J. D. Eaves, J. J. Loparo, A. Tokmakoff, P. L. Geissler, Science, 301,
1698-1702 (2003)
Obtaining absorptive line shapes in two-dimensional infrared vibrational
correlation spectra. M. Khalil, N. Demirdoven, A. Tokmakoff, Phys. Rev. Lett.,
90 (2003).
2002
Correlated vibrational dynamics revealed by two-dimensional infrared
spectroscopy. N. Demirdoven, M. Khalil, A. Tokmakoff, Phys. Rev. Lett., 89
(2002).
Isotropic and anisotropic Raman scattering from molecular liquids measured by
spatially masked optical Kerr effect spectroscopy. C. J. Fecko, J. D. Eaves, and
A. Tokmakoff, J. Chem. Phys., 117, 1139 (2002).
Dispersion compensation with optical materials for compression of intense
sub-100-fs mid-infrared pulses. N. Demirdoven, M. Khalil, O. Golonzka, and A.
Tokmakoff, Opt. Let., 27, 433 (2002).
2001
Coupling and orientation between anharmonic vibrations characterized with
two-dimensional infrared vibrational echo spectroscopy. O. Golonzka, M. Khalil,
N. Demirdven and A. Tokmakoff, J. Chem. Phys., 115, 10814 (2001).
Correlation effects in the two-dimensional vibrational spectroscopy of coupled
vibrations. N. Demirdven, M. Khalil, O. Golonzka and A. Tokmakoff, J. Phys.
Chem. A, 105, 8030 (2001).
Polarization-sensitive third-order spectroscopy of coupled vibronic states. O.
Golonzka and A. Tokmakoff, J. Chem. Phys., 115, 297(2001).
2000
Signatures of vibrational interactions in coherent two-dimensional infrared
spectroscopy. M. Khalil and A. Tokmakoff, Chem. Phys., Chem.l Phys., 266, 213
(2000).
Vibrational anharmonicities revealed by coherent two-dimensional infrared
spectroscopy. O. Golonzka, M. Khalil, N. Demirdoven and A. Tokmakoff, Phys. Rev.
Lett. 86, 2154 (2000).
Separation of cascaded and direct fifth-order Raman signals using
phase-sensitive intrinsic heterodyne detection. O. Golonzka, N. Demirdöven, M.
Khalil, and A. Tokmakoff, J. Chem. Phys., 113, 9893(2000).
Polarization-selective femtosecond Raman spectroscopy of isotropic and
anisotropic vibrational dynamics in liquids. M. Khalil, Oleg Golonzka, N.
Demirdöven, C. J. Fecko, and A. Tokmakoff, Chem. Phys. Lett., 321, 231 (2000).
A phase-sensitive detection method using diffractive optics for
polarization-selective femtosecond Raman spectroscopy. M. Khalil, N. Demirdöven,
Oleg Golonzka, C.J. Fecko, and A. Tokmakoff, J. Phys. Chem. A, 104, 5711(2000).
Two-dimensional lineshapes derived from coherent third-order nonlinear
spectroscopy. Andrei Tokmakoff, J. Phys. Chem. A, 104, 4247 (2000).
1999
Two-dimensional lineshape analysis of photon echo signal. Ko Okumura, Andrei
Tokmakoff, and Yoshitaka Tanimura, Chem. Phys. Lett, 314, 488 (1999).
Structural information from two-dimensional fifth order Raman spectroscopy. K.
Okumura, A. Tokmakoff, and Y. Tanimura, J. Chem. Phys, 111, 492 (1999).
1998
The intermolecular interaction mechanisms in liquid CS 2 at 299 K and 164 K
probed with two-dimensional Raman spectroscopy. A. Tokmakoff, M. J. Lang, X. S.
Jordanides and G. R. Fleming, Chem. Phys., 233, 231 (1998).
Examples of Ultrafast Dynamics Systems supplied by Del Mar Photonics:
Ultrafast Dynamics System
Del Mar Photonics offer complete Ultrafast Dynamics System. Examples of the table schematics is shown on the pictures:
Ultrafast Dynamics System includes:
Teahupoo Rider High Repetition Rate Amplified
Ti:Sapphire Laser
Beacon Up-Conversion Spectrometer
Hatteras Transient Absorption
Spectrometer
Femtosecond Harmonics
Generator
Teahupoo Rider and other options for Amplified
Ti:Sapphire Laser
1. We offer integrated oscillator/amplifier system
Teahupoo Rider. Teahupoo Rider is a fully-integrated all-in-one-box system
that includes Trestles Finesse oscillator
or Buccaneer SHG diode-pumped fiber oscillator,
pulse stretcher, regenerative amplifier pumped by
multi kHz Nd:YAG pump laser and pulse compressor. Teahupoo Rider has a
factory preinstalled repetition rate of 2, 5 or 10kHz and ideal for low cost
femtosecond micromachining systems, OPA pumping, ultrafast spectroscopy and
variety of applications in life sciences.
One-box system Trestles Finesse that include Trestles mini Ti:Sapphire oscillator and built in DPSS pump laser
When choosing specific Trestles Finesse model please indicate required CW pump power (4W or 6W), Ti:Sapphire pulse duration and required tuning range (or tuning range, where you want to achieve maximum performance)
Tuning range can be customized at the factory by choosing one of standard or custom made optics set. Typical tuning curves for 4W CW pump laser for two standard optics sets are shown in the Trestles Finesse brochure. For example, with 4W CW pump laser and long-wave mirrors set tuning range can be extended up to 940nm. With 6W CW pump laser tuning range can be extended up to 980nm.
2. If you already have a Ti:Sapphire oscillator, we can offer you stand alone Ti:Sapphire amplifier. Two standard models are available: Wedge M multipass or Wedge R regenerative.
Each amplifier is customized to the customer's amplifier pump laser.
2. Custom Teahupoo Rider systems with a pump
laser of your choice are also available. Depending on the required
specifications we can recommend a pump laser and make required adjustments for
optimum performance.
The following specifications can be achieved:
Repetition rate: single pulses, 10 Hz up to 10kHz
Pulse duration: 100fs, 50fs, 30fs, <30fs
Pulse energy: from 100 mJ per pulse to few mJ per
pulse
Tunability: both fixed wavelength and tunable options are available - please
indicate required tuning range.