Del Mar Photonics -
Research Associate in Coherent Laser Two Dimensional Infra-Red Spectroscopy of Proteins
Professor David Klug
Institute of Chemical Biology, Department of Chemistry, Imperial College London
1.5 years fixed term with a possible extension of another 12 months
We are seeking to appoint a Research Associate in Coherent Laser Two Dimensional Infra-Red Spectroscopy of Proteins. You will be working in collaboration with biochemists, cell biologists and chemists to further develop 2DIR methods for the analysis of oxidised proteins and other biomolecules for single cell and high throughput proteomic analysis. The research may also involve the study of protein-protein interactions. The successful candidate will be part of the Proxomics Project at the Institute of Chemical Biology, Imperial College London, and join a multidisciplinary team of researchers and students collaborating with members at University of Glasgow and Aston University, working on the development of new technologies for understanding the causes of ageing and protein-oxidative damage.
You must have a PhD in Physics or Physical Chemistry or a closely related discipline or equivalent research, industrial or commercial experience. The successful incumbent should also have experience in experimental non-linear optical spectroscopy, experimental ultrafast spectroscopy or experimental coherent multidimensional spectroscopy. Experience of and skills in the following would be desirable: practical optics and laser systems, design and development of analytical spectroscopic systems and tools, formal training in optics, design and development of non-linear spectroscopic apparatus, non-linear optical theory; and spectroscopic theory. Including experience and skills in: application of spectroscopy to analytical problems in biology; linear spectroscopic analysis; vibrational spectroscopy; spectroscopy of biological molecules; working and handling proteins.
You will also have experience of multidisciplinary research and working as part of a research team. You will have excellent verbal and written communication skills, and have the ability to produce clear, concise written material of a scientific nature. You will have the ability to organise your own work and prioritise it in response to deadlines. You must also be able to demonstrate a high level of computer literacy including word-processing, spreadsheets, and the internet.
femtosecond transient absorption data acquisition system
Future nanostructures and biological nanosystems will take advantage not only of the small dimensions of the objects but of the specific way of interaction between nano-objects. The interactions of building blocks within these nanosystems will be studied and optimized on the femtosecond time scale - says Sergey Egorov, President and CEO of Del Mar Photonics, Inc. Thus we put a lot of our efforts and resources into the development of new Ultrafast Dynamics Tools such as our Femtosecond Transient Absorption Measurements system Hatteras. Whether you want to create a new photovoltaic system that will efficiently convert photon energy in charge separation, or build a molecular complex that will dump photon energy into local heat to kill cancer cells, or create a new fluorescent probe for FRET microscopy, understanding of internal dynamics on femtosecond time scale is utterly important and requires advanced measurement techniques.
spot in our Ultrafast Dynamics Tools
training workshop in San Diego, California.
spot in our Ultrafast Dynamics Tools
training workshop in San Diego, California.
Product news and updates - Training Workshops - Featured Customer - Other News
Near Field Scanning Optical Microscope
NSOM Godwit - best spatial optical resolution using the near field scanning optical microscope
| Trestles LH Ti:Sapphire
Trestles LH is a new series of high quality femtosecond Ti:Sapphire lasers for applications in scientific research, biological imaging, life sciences and precision material processing. Trestles LH includes integrated sealed, turn-key, cost-effective, diode-pumped solid-state (DPSS). Trestles LH lasers offer the most attractive pricing on the market combined with excellent performance and reliability. DPSS LH is a state-of-the-art laser designed for today’s applications. It combines superb performance and tremendous value for today’s market and has numerous advantages over all other DPSS lasers suitable for Ti:Sapphire pumping. Trestles LH can be customized to fit customer requirements and budget.
Trestles LH plus OPO (Optical Parametric Oscillator)
DPSS DMPLH lasers
Pismo pulse picker
The Pismo pulse picker systems is as a pulse gating system that lets single pulses or group of subsequent pulses from a femtosecond or picosecond pulse train pass through the system, and stops other radiation. The system is perfectly suitable for most commercial femtosecond oscillators and amplifiers. The system can pick either single pulses, shoot bursts (patterns of single pulses) or pick group of subsequent pulses (wider square-shaped HV pulse modification). HV pulse duration (i.e. gate open time) is 10 ns in the default Pismo 8/1 model, but can be customized from 3 to 1250 ns upon request or made variable. The frequency of the picked pulses starts with single shot to 1 kHz for the basic model, and goes up to 100 kHz for the most advanced one.
The Pockels cell is supplied with a control unit that is capable of synching to the optical pulse train via a built-in photodetector unit, while electric trigger signal is also accepted. Two additional delay channels are available for synching of other equipment to the pulse picker operation. Moreover, USB connectivity and LabView-compatible drivers save a great deal of your time on storing and recalling presets, and setting up some automated experimental setups. One control unit is capable of driving of up to 3 Pockels cells, and this comes handy in complex setups or contrast-improving schemes. The system can also be modified to supply two HV pulses to one Pockels cell unit, making it a 2-channel pulse picker system. This may be essential for injection/ejection purposes when building a regenerative or multipass amplifier system.
Tourmaline Yb-SS-1058/100 Femtosecond solid state laser system
The Yb-doped Tourmaline Yb-SS laser radiates at 1058±2 nm with more than 1 W of average power, and enables the user to enjoy Ti:Sapphire level power at over-micron wavelengths. This new design from Del Mar's engineers features an integrated pump diode module for greater system stability and turn-key operation. The solid bulk body of the laser ensures maximum rigidity, while self-starting design provides for easy "plug-and-play" operation. Laser for second harmonic imaging in the retina with the voltage sensitive dye FM4-64
New fiber optics and fiber laser products
Laser Source for Photodynamic Therapy - request additional information and quote
AOM OEM Acousto-Optic Modulators for DPSS lasers, 1060 – 2100 nm - request additional information and quote
AOM – pigtailed for pulsed fiber lasers, 1060-2100 nm - request additional information and quote
Quasi-CW Yb fiber laser, 36 W in CW, 17 W pulsed - request additional information and quote
Pulsed (AOM) fiber laser, 20 W, 1060 – 2100 nm - request additional information and quote
Pulsed (pulse width/repetition rate – tunable) MOFA-type laser 10-W, 1060 nm - request additional information and quote
Eye-safe CW fiber laser, 25 W - request additional information and quote
Yellow fiber Laser, 15 W - request additional information and quote
10-GHz photonic link - request additional information and quote
780 nm and 1560 nm Femtosecond Fiber Laser
Buccaneer SHG 300/120
|New laser spectrometer
T&D-scan for research that
demands high resolution and high spectral
density in UV-VIS-NIR spectral domains - now available with
new pump option!
The T&D-scan includes a CW ultra-wide-tunable narrow-line laser, high-precision wavelength meter, an electronic control unit driven through USB interface as well as a software package. Novel advanced design of the fundamental laser component implements efficient intra-cavity frequency doubling as well as provides a state-of-the-art combined ultra-wide-tunable Ti:Sapphire & Dye laser capable of covering together a super-broad spectral range between 275 and 1100 nm. Wavelength selection components as well as the position of the non-linear crystal are precisely tuned by a closed-loop control system, which incorporates highly accurate wavelength meter.
Femtosecond fiber laser Model Pearl-70P300
request a quote
Femtosecond pulsed lasers are used in many fields of physics, biology, medicine and many other natural sciences and applications: material processing, multiphoton microscopy, «pump-probe» spectroscopy, parametric generation and optical frequency metrology. Femtosecond fiber lasers offer stable and steady operation without constant realignment.
The Pearl-70P300 laser comprises: a passively mode-locked fiber laser, providing pulses with repetition rate 60 MHz and having duration of 250-5000 fs, an amplifier based on Er3+ doped fiber waveguide with pumping by two laser diodes, a prism compressor for amplified pulse compression.
Pearl Ultra-Compact Ultrafast Picosecond Fiber Oscillator
Reef femtosecond autocorrelators
The autocorrelation technique is the most common method used to determine laser pulse width characteristics on a femtosecond time scale.
The basic optical configuration of the autocorrelator is similar to that of an interferometer (Figure.1). An incoming pulse train is split into two beams of equal intensity. An adjustable optical delay is inserted into one of the arms. The two beams are then recombined within a nonlinear material (semiconductor) for two photon absorption (TPA). The incident pulses directly generate a nonlinear TPA photocurrent in the semiconductor, and the detection of this photocurrent as a function of interferometer optical delay between the interacting pulses yields the pulse autocorrelation function. The TPA process is polarization-independent and non-phasematched, simplifying alignment.
Reef-RT autocorrelator measures laser pulse durations ranging from 20 femtoseconds to picosecond regime. It measures pulse widths from both low energy, high repetition rate oscillators and high energy, low repetition rate amplifiers. Compact control unit operates autocorrelator head and optional spectrometer through on-screen menus. Autocorrelation trace and spectrum can be displayed and analyzed on screen or downloaded to remote computer.
New: Reef-20DDR autocorrelator - Multishot-FROG for femtosecond fiber laser oscillator and amplifier
Collinear (interferometric) autocorrelation for 1300-2000 nm wavelength range
Trestles Fourth Harmonic Generator - request a quote
Trestles FHG is designed to work with Ti:sapphire lasers, such as the Trestles Ti:sapphire laser to provide fourth harmonic generation. Trestles FHG is an affordable and easy solution to generating pulses around 200 nm.
Trestles FHG is available in two versions. The first version uses the third harmonic mixed with the fundamental wavelength to produce fourth harmonic generation. This option provides the fundamental, as well as the second, third and fourth harmonics. For input of 810 nm, 1 W, 82MHz and 50 fs, output of the fourth harmonic is at 203 nm, 300-400 fs and power is 3 mW. The second option uses two separate second harmonic generation stages to produce fourth harmonic generation. With input of 810 nm, 1 W, 82 MHz and 50 fs, output of the fourth harmonic is at 210 nm, pulse width of 500 fs and power of 10 mW.
The Trestles FHG from Del Mar Photonics is an easily installed solution for adding functionality to any femtosecond laser system. Extended ranges will increase capabilities for research, and specific applications such as microscopy and spectroscopy.
Near IR viewers
Ultraviolet viewers are designed to observe radiation emitted by UV sources.
|Hummingbird EMCCD camera
The digital Hummingbird EMCCD camera combines high sensitivity, speed and high resolution.
It uses Texas Instruments' 1MegaPixel Frame Transfer Impactron device which provides QE up to 65%.
Hummingbird comes with a standard CameraLink output.
It is the smallest and most rugged 1MP EMCCD camera in the world.
It is ideally suited for any low imaging application such as hyperspectral imaging, X-ray imaging, Astronomy and low light surveillance.
It is small, lightweight, low power and is therefore the ideal camera for OEM and integrators.
|Come to San Diego next summer! Attend one of our training
workshops in San Diego, California during summer 2012
Del Mar Photonics has presented training workshops for customers and potential customers in the past 3 years.
Our workshops cover scientific basics, technical details and provide generous time for hands-on training.
Each workshop is a three-day seminar conducted by professional lecturer from 10am to 4pm. It includes lunch, as well as a training materials. We have also reserved two days for Q&A sessions, one-on-one system integration discussions, social networking, and San Diego sightseeing.
The following training workshops will be offered during this
Mar Photonics offers new
Trestles fs/CW laser system which can be easily
switched from femtosecond mode to CW and back. Having both modes of operation in one system dramatically increase a
number of applications that the laser can be used for, and makes it an ideal
tool for scientific lab involved in multiple research projects.
Frequency-stabilized CW single-frequency ring Dye laser DYE-SF-077 pumped by DPSS DMPLH laser installed in the brand new group of Dr. Dajun Wang at the The Chinese University of Hong Kong.
DYE-SF-077 features exceptionally narrow generation line width, which amounts to less than 100 kHz. DYE-SF-077 sets new standard for generation line width of commercial lasers. Prior to this model, the narrowest line-width of commercial dye lasers was as broad as 500 kHz - 1 MHz. It is necessary to note that the 100-kHz line-width is achieved in DYE-SF-077 without the use of an acousto-optical modulator, which, as a rule, complicates the design and introduces additional losses. A specially designed ultra-fast PZT is used for efficient suppression of radiation frequency fluctuations in a broad frequency range. DYE-SF-077 will be used in resaerch of Ultracold polar molecules, Bose-Einstein condensate and quantum degenerate Fermi gas and High resolution spectroscopy
Del Mar Photonics continuously expands its components portfolio.
|We are looking forward to hear from you and help you with your optical and crystal components requirements. Need time to think about it? Drop us a line and we'll send you beautiful Del Mar Photonics mug (or two) so you can have a tea party with your colleagues and discuss your potential needs.|
Del Mar Photonics, Inc.
4119 Twilight Ridge
San Diego, CA 92130
tel: (858) 876-3133
fax: (858) 630-2376